Distribution of Multilayered Fiber Terminals in the Human Cerebellar Cortex. Visualization by Immunohistochemistry for Histamine

A. Rizzi, M. Saccia, V. Benagiano
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引用次数: 1

Abstract

The distribution of histamine in the human cerebellar cortex was studied by light microscope immunohistochemistry using a rabbit polyclonal antibody anti-histamine. In all layers of the cerebellar cortex, were revealed punctate immunoreactive elements related to putative histaminergic nerve terminals. These findings provide insights into the existence of a histaminergic system in the human cerebellar cortex, presumably involved in the cerebrocerebellar circuit, the feedback circuit through which the cerebellum is widely connected with the neocortex and the hypothalamus and intervene in the regulation of motor and non-motor functions.
多层纤维终端在人类小脑皮层的分布。免疫组织化学显示组胺
用兔抗组胺多克隆抗体免疫组织化学方法研究了组胺在人小脑皮质的分布。在小脑皮层的所有层中,都发现了与假定的组胺能神经末梢有关的点状免疫反应元件。这些发现为人类小脑皮层中组胺能系统的存在提供了见解,该系统可能参与脑脑回路,小脑通过该反馈回路与新皮层和下丘脑广泛连接,并干预运动和非运动功能的调节。
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