Metabolic syndromes responsible for cervical cancer and advancement of nanocarriers for efficient targeted drug delivery- A review

IF 2 Q3 ONCOLOGY
Sumel Ashique , Aakash Upadhyay , Nitish Kumar , Sanjana Chauhan , Neeraj Mishra
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引用次数: 7

Abstract

Cervical cancer (CC), the fourth worldwide incessant malignant neoplasia particularly in women, emerged as a serious public health problem. Metabolic syndrome (MetS) is an accumulation of different threats aspects, which could eventually cause diabetes and cardiovascular disease as co-morbidity, further contributing to mortality that is detected by central obesity, dyslipidemia, hyperglycemia, and hypertension. Accumulatively, endemic as well as research data supports the notion of MetS increasing general malignancies occurrences, further contributing to mortality rate. Nano-scale drug delivery system, provide targeted drug delivery, increases drug absorption rates, while drug decomposition and systemic adverse effects get decreased. This article has described the different metabolic syndromes playing role in cervical cancer, alongside cervical cancer nanocarriers modern therapy.

宫颈癌的代谢综合征和高效靶向药物递送纳米载体的进展综述
宫颈癌(CC)是世界上第四大恶性肿瘤,特别是在妇女中,已成为一个严重的公共卫生问题。代谢综合征(MetS)是不同威胁因素的累积,最终可能导致糖尿病和心血管疾病合并症,进一步导致中枢性肥胖、血脂异常、高血糖和高血压检测到的死亡率。累积起来,地方性和研究数据支持MetS增加一般恶性肿瘤发生率的概念,进一步导致死亡率。纳米级给药系统,提供靶向给药,提高药物吸收率,同时减少药物分解和全身不良反应。本文介绍了不同的代谢综合征在宫颈癌中的作用,以及宫颈癌纳米载体的现代治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Advances in cancer biology - metastasis
Advances in cancer biology - metastasis Cancer Research, Oncology
CiteScore
2.40
自引率
0.00%
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0
审稿时长
103 days
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