Factors influencing adherence towards oral hypoglycaemic agents- A cross-sectional study among patients with Type II Diabetes Mellitus

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-10-01 DOI:10.1016/j.deman.2023.100163

Abhilash P , Delisha Josvita Dsouza , Sradha S , Nandakumar UP , Shuaib Ahmed MA , Reshma Kolar , Sharad Chand

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Abstract

Aims

The present study was conducted to assess the level of medication adherence and factors affecting adherence among Type-2 Diabetes Mellitus (T2DM) patients.

Methods

A prospective cross-sectional study was carried out among T2DM patients who were presented to the outpatient department of general medicine. A well-designed data collection form was used to gather information pertaining to various socio-demographic and medical variables. A previously validated and translated 8-item self-reported questionnaire was used to assess the level of medication adherence. Data was analysed using SPSS Version 29.0.

Results

Among the total 369 subjects enrolled, a majority were found to be males, and the mean age of the population was observed as 56.84 ± 11.32. A total of 125 (33.8%) subjects were found to be within the category of high adherence, 161 (43.6%) subjects were found to have moderate level of adherence and 83 (22.4%) had low level of adherence. On analysis, various medical variables were found to have a statistically significant association with medication adherence.

Conclusion

The findings of the present study would form the basis for all the future implications including education intervention programmes to improve the level of adherence towards anti-diabetic medications, which ultimately results in better health outcomes.

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影响口服降糖药依从性的因素- 2型糖尿病患者的横断面研究

目的探讨2型糖尿病(T2DM)患者的药物依从性水平及影响依从性的因素。方法对在普通内科门诊就诊的2型糖尿病患者进行前瞻性横断面研究。使用了设计良好的数据收集表来收集有关各种社会人口和医学变量的信息。先前经过验证和翻译的8项自我报告问卷用于评估药物依从性水平。数据分析采用SPSS 29.0版本。结果共入组369例，男性居多，平均年龄56.84±11.32岁。高依从性125人(33.8%)，中等依从性161人(43.6%)，低依从性83人(22.4%)。在分析中，发现各种医学变量与药物依从性有统计学上显著的关联。结论本研究的结果将为未来的教育干预计划提供基础，以提高抗糖尿病药物的依从性，最终达到更好的健康结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.