Leptospira bacteria detected in rodents in Tana River and Garissa counties of Kenya

Q1 Environmental Science

Infection Ecology and Epidemiology Pub Date : 2018-01-01 DOI:10.1080/20008686.2018.1547093

M. Wainaina, B. Bett, E. Ontiri, K. Picozzi, B. Agwanda, Tanja M. Strand, D. Grace, Å. Lundkvist, J. Lindahl

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引用次数: 2

Abstract

ABSTRACT Introduction: Leptospirosis is a bacterial zoonotic disease with wide geographical spread. Its presence in Kenya and some of the neighbouring countries has been documented before and it is thought to contribute significantly to the number of febrile cases in human populations and abortions in livestock. This study investigated Leptospira spp. presence in rodents collected in both a pastoral and irrigated region of Kenya. Materials and methods: Blood and kidney samples were screened for leptospiral DNA by PCR, and ELISA was used to detect antibodies in tissue fluid. Results and discussion: Almost 42% (28/67) of the rodents were found to be PCR positive and 25% (14/56) by the ELISA test. Focus group discussions revealed that the local population perceived an increase in the rodent population and febrile illnesses not responsive to malarial treatment, a possible attestation of importance of non-malarial acute febrile illnesses such as leptospirosis in the communities. Conclusion: While the study was small, it indicated that rodents could play an important role as reservoir hosts for the bacteria in these areas.

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肯尼亚塔纳河和加里萨县啮齿动物中检测到钩端螺旋体细菌

摘要简介:钩端螺旋体病是一种具有广泛地理分布的细菌性人畜共患疾病。它在肯尼亚和一些邻国的存在以前已被记录在案，并且被认为是造成人口发热病例和牲畜堕胎数量的重要原因。本研究调查了在肯尼亚牧区和灌区收集的啮齿动物中钩端螺旋体的存在。材料与方法:采用PCR法筛选血液和肾脏标本中钩端螺旋体DNA, ELISA法检测组织液中抗体。结果与讨论:PCR检测阳性率为42% (28/67)，ELISA检测阳性率为25%(14/56)。焦点小组讨论显示，当地居民认为啮齿动物种群和对疟疾治疗无反应的发热性疾病有所增加，这可能证明了社区中钩端螺旋体病等非疟疾急性发热性疾病的重要性。结论:本研究规模虽小，但提示啮齿动物可能在这些地区发挥重要的寄主作用。

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来源期刊

Infection Ecology and Epidemiology Environmental Science-Environmental Science (miscellaneous)

CiteScore

8.70

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： Infection Ecology & Epidemiology aims to stimulate inter-disciplinary collaborations dealing with a range of subjects, from the plethora of zoonotic infections in humans, over diseases with implication in wildlife ecology, to advanced virology and bacteriology. The journal specifically welcomes papers from studies where researchers from multiple medical and ecological disciplines are collaborating so as to increase our knowledge of the emergence, spread and effect of new and re-emerged infectious diseases in humans, domestic animals and wildlife. Main areas of interest include, but are not limited to: 1.Zoonotic microbioorganisms 2.Vector borne infections 3.Gastrointestinal pathogens 4.Antimicrobial resistance 5.Zoonotic microbioorganisms in changing environment