Chao-Feng Liao, S. Chuang, Hao-min Cheng, Chen-Huan Chen
{"title":"P.23 Relationship Between Aortic Stiffness, Aortic, and Carotid Impedance with Vascular Aging in Community-Based Healthy People","authors":"Chao-Feng Liao, S. Chuang, Hao-min Cheng, Chen-Huan Chen","doi":"10.2991/artres.k.201209.036","DOIUrl":null,"url":null,"abstract":"Background: Stiffening of the aorta has been associated with microvascular structural brain damage and cognitive dysfunction in cross-sectional and longitudinal studies, probably due to the reduced wave reflection at the interface between carotid and aorta and transmission of excessive flow pulsatility into the brain. The present study investigated whether age-related stiffening of the proximal aorta is disproportionately greater than the carotid arteries and whether the coupling of stiffness between proximal aorta and carotid arteries affects wave reflection at the interface.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.9000,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Artery Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2991/artres.k.201209.036","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Stiffening of the aorta has been associated with microvascular structural brain damage and cognitive dysfunction in cross-sectional and longitudinal studies, probably due to the reduced wave reflection at the interface between carotid and aorta and transmission of excessive flow pulsatility into the brain. The present study investigated whether age-related stiffening of the proximal aorta is disproportionately greater than the carotid arteries and whether the coupling of stiffness between proximal aorta and carotid arteries affects wave reflection at the interface.
Artery ResearchMedicine-Cardiology and Cardiovascular Medicine
CiteScore
1.70
自引率
16.70%
发文量
14
审稿时长
13 weeks
期刊介绍:
Artery Research is the official journal of the Association for Research into Arterial Structure and Physiology (ARTERY) which promotes the advancement of knowledge and dissemination of information concerning the pathophysiology, epidemiology, detection, investigation and treatment of arterial structure and function. The journal publishes original research articles, review articles, perspectives, case-studies, letters to the Editor, short communications and images. All submitted material is subject to a strict peer-review process.