Acceptability of Event-Driven and Long-Acting HIV Pre-Exposure Prophylaxis Formulations Among Transgender Women Engaged in Street-Based Sex Work in Baltimore, Maryland.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Applied Bio Materials Pub Date : 2024-04-03 eCollection Date: 2024-04-01 DOI:10.1089/trgh.2022.0057

Joseph G Rosen, S Wilson Beckham, Jennifer L Glick, Rebecca Hamilton White, Ju Nyeong Park, Katherine H A Footer, Susan G Sherman

引用次数: 0

Abstract

We assessed acceptability of nonoral HIV pre-exposure prophylaxis (PrEP) formulations among transgender women (TW) engaged in street-based sex work in Baltimore, Maryland. In a K-means cluster analysis, TW (N=36) were partitioned into groups characterized by high interest in long-acting injectable PrEP only (Injectable Enthusiasts, 36%), high interest in injectables and subdermal implants (Long-Acting Acceptors, 36%), and low interest across PrEP formulations (Non-Acceptors, 28%). TW's interest in novel PrEP agents varied widely across formulations (range: 22-66%) and clustered around numerous relational, occupational, and structural factors, highlighting the importance of availing multiple PrEP formulations for this impacted population.

查看原文本刊更多论文

马里兰州巴尔的摩市从事街头性工作的跨性别妇女对事件驱动和长效HIV暴露前预防制剂的可接受性

我们评估了马里兰州巴尔的摩市从事街头性工作的变性女性（TW）对非口服艾滋病暴露前预防（PrEP）制剂的接受程度。在 K-means 聚类分析中，变性女性（36 人）被分为以下几组：只对长效注射型 PrEP 感兴趣者（注射型狂热者，36%）、对注射型和皮下植入型兴趣者（长效型接受者，36%）和对各种 PrEP 制剂兴趣者（非接受者，28%）。TW 对各种新型 PrEP 制剂的兴趣差异很大（范围：22%-66%），并集中在许多关系、职业和结构因素上，这突显了为这一受影响人群提供多种 PrEP 制剂的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464

期刊介绍： ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.