The glucose level linkages with breast cancer markers

Abstract

The glucose level linkages with breast cancer (BC) biomarkers are focused in the article adopting probabilistic modeling with a real data set surveyed from 64 BC women and 52 normal women along with 10 interested study factors. It is derived that mean glucose levels are over for BC women (P=0.02224) than normal. Mean glucose levels are inversely linked with insulin (P< 0.00001), interaction effects of leptin and adiponectin (leptin*adiponectin) (P=0.08834), homeostasis model assessment score insulin resistance (HOMA-IR) and leptin (HOMA-IR*leptin) (P<0.00001), while they are directly linked with HOMA-IR (P<0.00001) and leptin (P<0.00001). The variance of glucose levels is inversely linked with leptin (P=0.00022), insulin (P=0.01365), monocyte chemoattractant protein-1 (MCP-1) (P=0.01153), insulin*HOMA-IR (P=0.00022), age*resistin (P=0.03974), age*HOMA-IR(P=0.03102), while it is directly linked with HOMA-IR (P<0.00001), resistin (P=0.02182) and age (P=0.00133). Glucose levels are higher for BC women, and they increase along with the increased levels of HOMA-IR, leptin, and the decreased levels of insulin, HOMA-IR*leptin, leptin*adiponectin.