Ependymoma as a Secondary Malignancy after Treatment of Non- Hodgkin Lymphoma

Abstract

Therapeutic advances in the treatment of paediatric neoplasms have improved the prognosis but have also increased the risk of developing rare second malignant neoplasms (SMNs) in late period after chemotherapy or radiation course. We are going to report a patient therapy-related solid tumors (brain ependymoma after non Hodgkin lymphoma) short latency period after primary tumor which is a rare case among secondary tumors. After 4 years from lymphoma involvement a mediastinal mass revealed in CXR in favor of relapse in follow up period. The key point of this case is that secondary solid malignancy followed infiltrative malignancy despite of similar cases that infiltrative malignancy followed solid tumor and without radiation therapy.