Potential of ultrasound in the evaluation of acute appendicitis during pregnancy: a systematic review and meta-analysis

IF 0.4 4区医学 Q4 OBSTETRICS & GYNECOLOGY

Clinical and experimental obstetrics & gynecology Pub Date : 2022-01-12 DOI:10.31083/j.ceog4901015

Yunlong Li, Shikuan Li

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Abstract

Objective: To assess the accuracy of ultrasound in diagnosing acute appendicitis in pregnant women. Mechanism: The National Library of Medicine (MEDLINE, 1990–2020), Excerpta Medica Database (EMBASE,1946–2020) and the Cochrane Controlled Trials Register (CENTRAL)were used to extract articles that were published in English. A total of five studies involving 521 patients were selected. The DerSimonian and Laird random-effects model and Quality Assessment Tool for Diagnostic Accuracy (QUADAS-2) were used to analyze the data. Findings in brief: We identified 140 related articles and included 5 articles enrolling 521 patients. The values obtained using ultrasound for appendicitis during pregnancy were sensitivity of 0.62 (95% Confidence interval (CI): 0.43–0.78), the specificity of 0.91 (95% CI: 0.74–0.97), and the Positive Likelihood Ratio of 7.0 (95% CI: 2.5–19.7), the Negative Likelihood Ratio of 0.41 (95% CI: 0.27–0.63) and the Diagnostic Odds Ratio of 17 (95% CI : 6–49). Conclusion: Ultrasound had medium-level sensitivity and high specificity for the diagnosis of appendicitis in pregnant women.

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超声在评估妊娠期急性阑尾炎中的潜力：系统综述和荟萃分析

目的：评价超声诊断孕妇急性阑尾炎的准确性。机制：国家医学图书馆（MEDLINE，1990–2020）、医学数据库摘录（EMBASE，1946–2020）和Cochrane对照试验登记册（CENTRAL）用于提取以英语发表的文章。共选择了5项研究，涉及521名患者。使用DerSimonian和Laird随机效应模型和诊断准确性质量评估工具（QUADAS-2）对数据进行分析。研究结果简言之：我们确定了140篇相关文章，其中包括5篇涉及521名患者的文章。妊娠期阑尾炎超声诊断的敏感性为0.62（95%置信区间：0.43-0.78），特异性为0.91（95%CI:0.74-0.97），阳性似然比为7.0（95%CI:2.5-19.7），阴性似然比为0.41（95%CI:0.27-0.63），诊断比值比为17（95%CI:6-49）。结论：超声诊断孕妇阑尾炎具有中等程度的敏感性和较高的特异性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical and experimental obstetrics & gynecology 医学-妇产科学

CiteScore

0.50

自引率

0.00%

发文量

241

审稿时长

1 months

期刊介绍： CEOG is an international, peer-reviewed, open access journal. CEOG covers all aspects of Obstetrics and Gynecology, including obstetrics, prenatal diagnosis, maternal-fetal medicine, perinatology, general gynecology, gynecologic oncology, uro-gynecology, reproductive medicine, infertility, reproductive endocrinology, sexual medicine. All submissions of cutting-edge advances of medical research in the area of women''s health worldwide are encouraged.