Curcumin-Impregnated Drug Delivery Systems May Show Promise in the Treatment of Diseases Secondary to Traumatic Brain Injury: Systematic Review

IF 0.4 Q4 PHARMACOLOGY & PHARMACY
I. Yilmaz, N. Karaarslan, H. Somay, H. Ozbek, O. Ates
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引用次数: 0

Abstract

Objective To find out whether curcumin can be effective in the treatment of traumatic brain injury (TBI). Methods A comprehensive and systematic literature search in the PubMed electronic database was performed. Descriptive statistics were used to evaluate the data obtained. The results were presented as frequency and percentage (%) or amount. Results Two clinical trials investigated curcumin for the treatment of TBI. One study tested curcumin in living mammalian subjects using an amyloLipid nanovesicle. In three studies, curcumin was investigated together with the drug delivery system for the treatment of TBI. Conclusion Drug delivery systems prepared with nanomaterials may have a potential therapeutic effect in treating TBI by increasing neuroprotection because they can penetrate the central nervous system more rapidly.
姜黄素浸渍给药系统可能在治疗创伤性脑损伤继发疾病方面显示出前景:系统综述
目的探讨姜黄素治疗创伤性脑损伤(TBI)的疗效。方法在PubMed电子数据库中进行全面、系统的文献检索。使用描述性统计对所获得的数据进行评估。结果以频率和百分比(%)或数量表示。结果两项临床试验研究了姜黄素治疗创伤性脑损伤的疗效。一项研究使用淀粉脂质纳米囊泡在活体哺乳动物中测试姜黄素。在三项研究中,姜黄素与药物递送系统一起用于治疗TBI。结论用纳米材料制备的药物递送系统可以更快地穿透中枢神经系统,通过增加神经保护作用,对治疗创伤性脑损伤具有潜在的治疗作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.40
自引率
0.00%
发文量
37
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