Evaluation of skeletal muscle perfusion in a canine hindlimb ischemia model using CT perfusion imaging.

IF 2.1 4区医学 Q2 Medicine

Diagnostic and Interventional Radiology Pub Date : 2020-01-02 DOI:10.5152/dir.2019.18478

Tao Wang, H. Su, J. Gu, Qian Chen, Quanxue Xu, Bihong T. Chen

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引用次数: 1

Abstract

PURPOSE To evaluate skeletal muscle perfusion in a canine hind limb ischemia model using CT perfusion imaging (CTPI). METHODS Twelve beagles underwent embolization at the branch of the left deep femoral artery. The right hind limbs were used as controls. CTPI was performed immediately after embolization. The perfusion parameters of the regions of interest (ROI), including blood volume (BV), blood flow (BF), mean transit time (MTT) and permeability (PMB), were obtained in both the lateral and posterior hind limb muscle groups. RESULTS After embolization, the BV, BF and PMB values in the lateral muscles of the left hind limbs were significantly lower than those in the right hind limbs (P > 0.05), and the MTT was significantly prolonged (P > 0.05). The values for BV, BF, MTT and PMB in the posterior muscles of the left hind limbs were not significantly different from those in the right hind limbs (P > 0.05). The values for BV, BF and PMB in the lateral muscles of the left hind limbs were significantly lower than those in the posterior muscles of the left hind limbs (P > 0.05).

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使用CT灌注成像评估犬后肢缺血模型中的骨骼肌灌注。

目的应用CT灌注成像（CTPI）评价犬后肢缺血模型中骨骼肌的灌注情况。右后肢作为对照。栓塞后立即进行CTPI。在后肢外侧和后侧肌肉组中获得感兴趣区域（ROI）的灌注参数，包括血容量（BV）、血流量（BF）、平均通过时间（MTT）和通透性（PMB）。结果栓塞后左后肢外侧肌BV、BF和PMB值均显著低于右后肢（P>0.05），MTT值显著延长（P>0.05），左后肢后肌MTT和PMB与右后肢无显著性差异（P>0.05），左后肢外侧肌BV、BF和PMB显著低于左后肢后肌肉（P>0.05）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diagnostic and Interventional Radiology 医学-核医学

CiteScore

3.50

自引率

4.80%

发文量

审稿时长

6-12 weeks

期刊介绍： Diagnostic and Interventional Radiology (Diagn Interv Radiol) is the open access, online-only official publication of Turkish Society of Radiology. It is published bimonthly and the journal’s publication language is English. The journal is a medium for original articles, reviews, pictorial essays, technical notes related to all fields of diagnostic and interventional radiology.