Recommendations for the diagnosis and management of persons with suspected vaccine-induced immune thrombotic thrombocytopenia (VITT)

Q3 Medicine
Infectio Pub Date : 2021-08-14 DOI:10.22354/in.v26i1.987
N. Yomayusa, J. Acevedo, Virginia Abello Polo, R. Izaguirre, C. Ramírez, M. Solano, S. Ramírez, Patricia Rodríguez, Lina Morón, Ilich Herbert De La Hoz, Kelly Rocio Chacón, P. Gutiérrez, C. Agudelo, Sonia Hernández, G. León, J. Accini, Gerardo Rodríguez Ortíz, A. Concha-Mejía, R. Contreras, Bibiana Escobar, T. Espinosa, C. González, Erica Yama, G. Aroca, Cecilia Guillermo, O. Hamann, Laura Horlandy, Claudia Moreno, N. Mejia, Fernán Mendoza, Jeffrey Castellanos, J. Rozo, Camilo Montero, J. Navarro, J. Oñate, D. Pinto, N. Restrepo, Oscar Sáenz, Lina Triana, Liliana Correa, L. Sabbagh, Ana Castillo, R. Torres, Alberto Lineros
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引用次数: 1

Abstract

In recent months, rare cases of thrombosis at unusual sites associated with thrombocytopenia, occurring within a typical risk window (i.e., 4-28 days) after receiving SARS CoV2 vaccines, have been reported. Healthcare professionals should be prepared to detect these cases on time. The Expert Panel of the Knowledge Management and Transfer Network conducted a free search of the related literature. With the available information and the clinical expertise of the working group, we formulated, reviewed, and endorsed recommendations for the timely suspicion, diagnosis (case definitions, the use of initial laboratory and imaging tests, specific tests), and management of these thrombotic conditions. This document is considered a living document that will be updated as new evidence emerges, and recommendations may change over time.
对疑似疫苗引起的免疫性血栓性血小板减少症(VITT)患者的诊断和管理建议
最近几个月,在接受SARS CoV2疫苗后的典型风险窗口(即4-28天)内,报告了与血小板减少症相关的罕见血栓形成病例。医疗保健专业人员应做好及时发现这些病例的准备。知识管理与转移网络专家小组对相关文献进行了免费检索。根据现有信息和工作组的临床专业知识,我们制定、审查并批准了及时怀疑、诊断(病例定义、初始实验室和影像学检查的使用、特定检查)和管理这些血栓性疾病的建议。本文件被认为是一份活文件,将随着新证据的出现而更新,建议可能会随着时间的推移而改变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Infectio
Infectio Medicine-Pharmacology (medical)
CiteScore
1.50
自引率
0.00%
发文量
18
审稿时长
39 weeks
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