Anoop V Somarajan, Athira Mohan, Ahamed Shabeer, RS Anusreeraj
{"title":"Immune Thrombocytopenic Purpura: A Case Report","authors":"Anoop V Somarajan, Athira Mohan, Ahamed Shabeer, RS Anusreeraj","doi":"10.52793/jscr.2021.3(3)-36","DOIUrl":null,"url":null,"abstract":"Immune Thrombocytopenic Purpura also known as Idiopathic Thrombocytopenic Purpura or ITP, is an autoimmune disorder characterised by accelerated destruction and suboptimal platelet production that leads to reduced peripheral blood platelet counts. Females have a higher incidence than in Males with the ratio of 3:1. Here we present a case of 68-year-old female, with complaints of purpuric spots, ecchymosis, discolouration of tongue and history of melena. The treatment is initiated with IV dose of Corticosteroids followed by platelet infusions. Steroid dose must be tapered after one month of treatment schedule. Splenectomy is preferred in severe cases. ITP occurs because of platelet destruction abruptly by complex mechanisms in the immune system.","PeriodicalId":92258,"journal":{"name":"Journal of stem cell research","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of stem cell research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52793/jscr.2021.3(3)-36","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Immune Thrombocytopenic Purpura also known as Idiopathic Thrombocytopenic Purpura or ITP, is an autoimmune disorder characterised by accelerated destruction and suboptimal platelet production that leads to reduced peripheral blood platelet counts. Females have a higher incidence than in Males with the ratio of 3:1. Here we present a case of 68-year-old female, with complaints of purpuric spots, ecchymosis, discolouration of tongue and history of melena. The treatment is initiated with IV dose of Corticosteroids followed by platelet infusions. Steroid dose must be tapered after one month of treatment schedule. Splenectomy is preferred in severe cases. ITP occurs because of platelet destruction abruptly by complex mechanisms in the immune system.