Review on computational modeling for the property, process, product and performance (PPPP) characteristics of additively manufactured porous magnesium implants

Q1 Computer Science
Ramsha Imran , Ans Al Rashid , Muammer Koç
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引用次数: 17

Abstract

Recently, magnesium (Mg) and its alloys are gaining the attention of researchers as these materials can provide mechanical properties comparable to natural bone. Additive manufacturing (AM) techniques have also evolved in the biomedical sector owing to their precision in fabricating desired parts with varying shapes, intricacy, and porosity required for implant functionality. With increasing interest in AM of Mg-based biomedical implants, there is a pressing need to understand existing accomplishments, state-of-the-art materials, and fabrication technology and to identify remaining research gaps through a comprehensive literature review existing in this field and highlight hindrances and challenges associated. In this review study, a particular focus is placed on understanding computational modeling techniques employed for the design, manufacturing, and performance analysis of AM porous scaffolds. Therefore, progress in material synthesis and associated challenges are reviewed in this study, and conclusions and future research recommendations are drawn based on reviewed literature. This review study concludes that there is an unmet need to develop accurate, fast, and inexpensive computational modeling for AM of Mg-based implants to increase predictability capacity and capabilities of material synthesis, fabrication, and resulting product property and performance.

Abstract Image

添加制造的多孔镁植入物的性能、工艺、产品和性能(PPPP)特征的计算模型综述
最近,镁(Mg)及其合金正在引起研究人员的注意,因为这些材料可以提供与天然骨相当的机械性能。增材制造(AM)技术在生物医学领域也得到了发展,因为它们可以精确地制造出具有不同形状、复杂性和植入功能所需孔隙度的所需部件。随着人们对镁基生物医学植入物增材制造的兴趣日益浓厚,迫切需要了解现有的成就、最先进的材料和制造技术,并通过对该领域现有文献的全面回顾来确定剩余的研究差距,并突出相关的障碍和挑战。在这篇综述研究中,特别关注的是理解用于AM多孔支架设计、制造和性能分析的计算建模技术。因此,本研究综述了材料合成的进展和相关挑战,并在综述文献的基础上提出结论和未来的研究建议。本综述的结论是,开发准确、快速、廉价的镁基植入物增材制造计算模型,以提高材料合成、制造和最终产品性能的可预测性能力和能力,这一需求尚未得到满足。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Bioprinting
Bioprinting Computer Science-Computer Science Applications
CiteScore
11.50
自引率
0.00%
发文量
72
审稿时长
68 days
期刊介绍: Bioprinting is a broad-spectrum, multidisciplinary journal that covers all aspects of 3D fabrication technology involving biological tissues, organs and cells for medical and biotechnology applications. Topics covered include nanomaterials, biomaterials, scaffolds, 3D printing technology, imaging and CAD/CAM software and hardware, post-printing bioreactor maturation, cell and biological factor patterning, biofabrication, tissue engineering and other applications of 3D bioprinting technology. Bioprinting publishes research reports describing novel results with high clinical significance in all areas of 3D bioprinting research. Bioprinting issues contain a wide variety of review and analysis articles covering topics relevant to 3D bioprinting ranging from basic biological, material and technical advances to pre-clinical and clinical applications of 3D bioprinting.
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