Standing on the shoulders of giants: James Watson, Francis Crick, Maurice Wilkins, Rosalind Franklin and the birth of molecular biology

Q4 Biochemistry, Genetics and Molecular Biology
T. Danylova, S. Komisarenko
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引用次数: 8

Abstract

In the 20th century, DNa became a magnet, attracting representatives of various sciences. Prominent researchers competed among themselves to discover the structure of DNa and to explain the mechanisms that determine our “natural fate”, i.e., our heredity. an american chemist, biochemist, chemical engineer linus Pauling, a British physicist and molecular biologist maurice Wilkins, a British chemist, biophysicist, and X-ray crystallographer rosalind Franklin, an american geneticist, molecular biologist, zoologist James Watson, a British molecular biologist, biophysicist, and neuroscientist Francis Crick were among them. They searched for the scientific explanation for the enigma of life hidden in DNA. An accurate description of DNA double-helical structure belongs to James Watson and Francis Crick. However, the missing pieces of the puzzle were elaborated by Rosalind Franklin, who was not given enough credit for her dedicated scientific work. Unlike her, Francis Crick, James Watson, and maurice Wilkins were awarded the Nobel Prize in Physiology or Medicine 1962 for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material. Whatever the DNA story is, it shows that all great scientific discoveries are not made from scratch. The immense number of people have contributed to the development of science and literally every researcher stands on the shoulders of giants, while the idea itself is in the air. The discovery of the structure of DNA became a cornerstone for the new scientific paradigm – biology acquired a molecular and biochemical basis.
站在巨人的肩膀上:詹姆斯·沃森、弗朗西斯·克里克、莫里斯·威尔金斯、罗莎琳德·富兰克林和分子生物学的诞生
在20世纪,DNa就像一块磁铁,吸引着各种科学的代表。杰出的研究人员相互竞争,以发现DNa的结构,并解释决定我们“自然命运”的机制,即我们的遗传。美国化学家、生物化学家、化学工程师莱纳斯·鲍林,英国物理学家、分子生物学家莫里斯·威尔金斯,英国化学家、生物物理学家和x射线晶体学家罗莎琳德·富兰克林,美国遗传学家、分子生物学家、动物学家詹姆斯·沃森,英国分子生物学家、生物物理学家和神经学家弗朗西斯·克里克。他们寻找隐藏在DNA中的生命之谜的科学解释。对DNA双螺旋结构的准确描述属于詹姆斯·沃森和弗朗西斯·克里克。然而,罗莎琳德·富兰克林(Rosalind Franklin)阐述了这个谜题中缺失的部分,她的敬业科学工作没有得到足够的赞誉。与她不同的是,弗朗西斯·克里克、詹姆斯·沃森和莫里斯·威尔金斯因发现核酸的分子结构及其对生物物质信息传递的重要性而获得1962年诺贝尔生理学或医学奖。无论DNA的故事是什么,它都表明,所有伟大的科学发现都不是从零开始的。无数的人为科学的发展做出了贡献,实际上每个研究人员都站在巨人的肩膀上,而思想本身却在空中。DNA结构的发现成为新的科学范式的基石——生物学获得了分子和生化基础。
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来源期刊
Ukrainian Biochemical Journal
Ukrainian Biochemical Journal Biochemistry, Genetics and Molecular Biology-Biochemistry
CiteScore
1.20
自引率
0.00%
发文量
37
审稿时长
16 weeks
期刊介绍: The Ukrainian Biochemical Journal publishes original research papers, reviews and brief notes; papers on research methods and techniques; articles on the history of biochemistry, its development and prominent figures; discussion articles; book reviews; chronicles; etc. The journal scope includes not only biochemistry but also related sciences, such as cellular and molecular biology, bioorganic chemistry, biophysics, pharmacology, genetics, and medicine (medical biochemistry et al.) – insofar as the studies use biochemical methods and discuss biochemical findings.
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