Enfermedad pulmonar intersticial en el lupus eritematoso sistémico: búsqueda avanzada

Q3 Health Professions

Revista Colombiana de Reumatologia Pub Date : 2024-04-01 DOI:10.1016/j.rcreu.2022.10.004

Juan Camilo Santacruz, Marta Juliana Mantilla, Gustavo Rodríguez-Salas, Igor Rueda, Ana María Santos, John Londoño

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引用次数: 0

Abstract

Interstitial lung disease in lupus is an entity that occurs infrequently and tends to progress slowly in most cases. Despite this, the therapeutic approach for moderate to severe cases is largely unknown because most of the evidence comes from case reports, many of which predate the advent of today's known treatments for lupus. Additionally, little progress has been made in understanding its pathophysiology and current concepts come from other connective tissue diseases such as systemic sclerosis or are grouped within the group of interstitial pneumonias with autoimmune characteristics. This, to an extent, has been an obstacle for research in this field, and to date there is no unified diagnostic and therapeutic approach. Therefore we conducted a state of the art search of the best evidence available to date, in terms of diagnostic methods and emerging therapies, to offer the clinician a practical vision for a comprehensive approach.

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系统性红斑狼疮间质性肺疾病:高级搜索

狼疮间质性肺病是一种不常发生的疾病，在大多数病例中往往进展缓慢。尽管如此，中度至重度病例的治疗方法在很大程度上仍是未知数，因为大多数证据都来自病例报告，其中许多都是在当今已知的狼疮治疗方法出现之前。此外，人们对狼疮病理生理学的认识进展甚微，目前的概念来自于其他结缔组织疾病（如系统性硬化症）或具有自身免疫特征的间质性肺炎。这在一定程度上阻碍了该领域的研究，迄今为止还没有统一的诊断和治疗方法。因此，我们从诊断方法和新兴疗法两方面对迄今为止的最佳证据进行了一次最先进的搜索，以便为临床医生提供一种切实可行的综合方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista Colombiana de Reumatologia Medicine-Rheumatology

CiteScore

0.80

自引率

0.00%

发文量

期刊介绍： The Colombian Journal of Rheumatology (Revista Colombiana de Reumatología) is the official organ of the Colombian Association of Rheumatology (Asociación Colombiana de Reumatología) and the Central American, Caribbean and Andean Association of Rheumatology (Asociación Centroamericana Caribe Andina de Reumatología) - ACCA. It was created in December 1993 with the purpose of disseminating scientific information derived from primary and secondary research and presenting cases coming from the practice of Rheumatology in Latin America. Since its foundation, the Journal has been characterized by its plurality with subjects of all rheumatic and osteomuscular pathologies, in the form of original articles, historical articles, economic evaluations, and articles of reflection and education in Medicine. It covers an extensive area of topics ranging from the broad spectrum of the clinical aspects of rheumatology and related areas in autoimmunity (both in pediatric and adult pathologies), to aspects of basic sciences. It is an academic tool for the different members of the academic and scientific community at their different levels of training, from undergraduate to post-doctoral degrees, managing to integrate all actors inter and trans disciplinarily. It is intended for rheumatologists, general internists, specialists in related areas, and general practitioners in the country and abroad. It has become an important space in the work of all rheumatologists from Central and South America.