A review of the possible effects of curcumin in the treatment of COVID-19

Q3 Medicine

Journal of Military Medicine Pub Date : 2020-12-19 DOI:10.30491/JMM.22.11.1171

A. vahedian-azimi, S. Hosseini, Farshid Rahimibashar, A. Sahebkar

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引用次数: 0

Abstract

COVID-19, which is caused by the SARS-Cov-2, begins with early symptoms of fever, cough, shortness of breath, myalgia, and fatigue, affecting the lungs with pneumonia and causing acute respiratory distress syndrome (ARDS) Also, the onset of the disease may with rapid progression, lead to organ dysfunction, such as acute kidney or liver damage, and even death in severe cases Many scientific efforts are underway around the world to identify the appropriate treatment for this disease Curcumin is a natural polyphenolic compound, which could be a potential treatment option for patients with Covid-19 In this study, we review some of the possible effects of curcumin, such as inhibiting virus entry into the cell, inhibiting virus replication and viral protease, as well as modulating some intracellular messenger pathways To comprehensive literature review, information from an internet search of English language databases PubMed, Scopus, Web of Science and ScienceDirect as well as Persian language databases such as SID using related keywords based on MESH such as COVID-19, SARS-COV-2, Curcumin and curcuminoid between January 2020 and January 2021 were collected This review provides some possible effects of curcumin and its mechanisms for the treatment of COVID-19

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姜黄素治疗COVID-19可能作用的综述

由SARS-Cov-2引起的新冠肺炎最初出现发烧、咳嗽、气短、肌痛和疲劳的早期症状，肺炎影响肺部并导致急性呼吸窘迫综合征（ARDS），甚至在重症病例中死亡世界各地正在进行许多科学努力，以确定这种疾病的适当治疗方法姜黄素是一种天然多酚化合物，可能是新冠肺炎患者的潜在治疗选择。在这项研究中，我们回顾了姜黄素的一些可能作用，如抑制病毒进入细胞，抑制病毒复制和病毒蛋白酶，以及调节一些细胞内信使途径综合文献综述，来自英语数据库PubMed、Scopus、Web of Science和ScienceDirect以及波斯语数据库（如SID）的互联网搜索信息，使用基于MESH的相关关键词，如新冠肺炎、SARS-COV-2，收集了2020年1月至2021年1月期间的姜黄素和姜黄素。这篇综述提供了姜黄素治疗新冠肺炎的一些可能效果及其机制

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Military Medicine Medicine-Public Health, Environmental and Occupational Health

CiteScore

2.60

自引率

0.00%

发文量

期刊介绍： Journal of Military Medicine is a Bimonthly peer-reviewed medical journal covering research and developments in the field of health and medicine in military and crisis settings. The journal was established in 1999. It publishes original research reports, editorials, letters to the editor, and reviews.