Maternal Serum Ferritin Level in Prediction of Mothers with Appropriate-For-Gestational-Age (AGA), Small-For-Gestational Age (SGA), and Intrauterine Growth Restriction (IUGR)

IF 1.3 Q3 PEDIATRICS

International Journal of Pediatrics Pub Date : 2021-07-01 DOI:10.22038/IJP.2021.57318.4496

Tahereh Behrouzi-Lak, M. Mortazavi, Shabnam Vazifeshenas

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引用次数: 0

Abstract

Background Fetal growth restriction is one of the main causes of perinatal mortality that can be predicted by ferritin. We aimed to evaluate the role of ferritin in prediction of mothers with Appropriate-for-gestational-age (AGA), Small-for-gestational age (SGA) and intrauterine growth restriction (IUGR). Materials and Methods: In this cohort study, we screened 73 mothers with gestational ages of 32-34 weeks. If amniotic fluid index (AFI) was normal and there was no circulation defect, the fetuses were classified in SGA group and in case of presence of oligohydramnios or circulation defect; they were classified in IUGR group. Also, fetuses with normal growth were classified in AGA group. We evaluated the serum ferritin, hemoglobin, and iron of the mothers. Moreover, we evaluated the levels of placenta ferritin, Hb, and hematocrit in the delivery room. Results: In this study, 28 patients were categorized in AGA group, 15 patients in SGA group and 30 patients in IUGR group. Mean weight of all infants was 2210.60 ± 932.77 grams. Also, the mean AFI of all infants was 9.81 ± 3.59. The mean ferritin level of all mothers was 30.29 ± 10.80 and IUGR group had the highest and AGA group had the lowest ferritin levels (P=0.015). Maternal ferritin (µg/l) (Sen: 67.9%, Sp: 61.9%), maternal hematocrit (%) (Sen: 70%; Sp: 62.8%,) and maternal Hb (Sen: 70%, Sp: 65.1%,) could predict IUGR. Conclusion Increased (>34 µg/l) and decreased (

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血清铁蛋白水平对适胎龄(AGA)、小胎龄(SGA)和宫内生长受限(IUGR)孕妇的预测价值

胎儿生长受限是围产期死亡的主要原因之一，可通过铁蛋白预测。我们的目的是评估铁蛋白在预测适宜胎龄(AGA)、小胎龄(SGA)和宫内生长受限(IUGR)母亲中的作用。材料与方法:在本队列研究中，我们筛选了73位孕周32-34周的母亲。若羊水指数(羊水指数)正常且无循环缺陷，则归为SGA组，若存在羊水过少或循环缺陷;归类为IUGR组。将发育正常的胎儿分为AGA组。我们评估了母亲的血清铁蛋白、血红蛋白和铁。此外，我们还评估了产房中胎盘铁蛋白、血红蛋白和红细胞压积的水平。结果:本研究将28例患者分为AGA组，15例分为SGA组，30例分为IUGR组。婴儿平均体重2210.60±932.77 g。所有婴儿的平均AFI为9.81±3.59。所有母亲的平均铁蛋白水平为30.29±10.80，其中IUGR组最高，AGA组最低(P=0.015)。母体铁蛋白(µg/l) (Sen: 67.9%， Sp: 61.9%)，母体红细胞压积(%)(Sen: 70%;Sp: 62.8%，)和母体Hb (Sen: 70%， Sp: 65.1%，)可以预测IUGR。结论血氧浓度升高(>34µg/l)，降低(

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来源期刊

International Journal of Pediatrics PEDIATRICS-

CiteScore

3.90

自引率

0.00%

发文量

审稿时长

4 weeks

期刊介绍： International Journal of Pediatrics is a peer-reviewed, open access journal that publishes original researcharticles, review articles, and clinical studies in all areas of pediatric research. The journal accepts submissions presented as an original article, short communication, case report, review article, systematic review, or letter to the editor.