Investigating Relations Between the Symptoms of Panic, Agoraphobia, and Suicidal Ideation: The Significance of Comorbid Depressive Symptoms in Veterans with Panic Disorder.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2023-12-01 Epub Date: 2023-08-28 DOI:10.1007/s10862-023-10082-4
Daniel F Gros, Jeffrey M Pavlacic, Jennifer M Wray, Derek D Szafranski
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引用次数: 0

Abstract

Although panic disorder has been frequently associated with increased suicidal ideation and behaviors, there are multiple explanations for this association in the literature. For example, some research has demonstrated panic disorder symptoms to mediate agoraphobia and suicidal ideation, while other researchers have hypothesized that comorbid depression symptoms contribute to suicidal ideation across anxiety disorders. Of note, none of these studies were completed in veterans, a population at higher risk for suicide relative to civilian samples. The present study investigated relations between the symptoms of panic, agoraphobia, depression, and suicidal ideation in 58 veterans diagnosed with panic disorder via correlations, hierarchical regression, and exploratory path analyses. Multiple models were investigated based on prior research. The final path model demonstrated that symptoms of panic disorder predicted agoraphobia symptoms, with agoraphobia predicting symptoms of depression. Symptoms of depression, then, predicted suicidal ideation. Discussion of the findings related to comorbid depressive symptoms highlight considerations for the assessment and treatment practices for panic disorder, with a particular focus on veterans receiving care within Veterans Affairs Healthcare System.

惊恐、广场恐怖和自杀意念之间的关系:退伍军人惊恐障碍共病抑郁症状的意义
虽然惊恐障碍经常与自杀意念和行为的增加有关,但文献中对这种关联有多种解释。例如,一些研究表明恐慌症症状是恐旷症和自杀意念的中介,而另一些研究人员则假设,合并抑郁症状会导致焦虑症患者产生自杀意念。值得注意的是,这些研究都不是针对退伍军人完成的,而相对于平民样本,退伍军人的自杀风险更高。本研究通过相关性分析、分层回归分析和探索性路径分析,调查了 58 名被诊断患有惊恐障碍的退伍军人的惊恐、惧高症、抑郁症状和自杀意念之间的关系。根据先前的研究,对多个模型进行了研究。最终的路径模型表明,恐慌症症状可预测惧旷症症状,而惧旷症可预测抑郁症症状。抑郁症状则预示着自杀意念。与合并抑郁症状相关的研究结果讨论强调了恐慌症评估和治疗实践中的注意事项,尤其关注在退伍军人事务医疗保健系统内接受治疗的退伍军人。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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