A review on additive manufacturing of lattice structures in tissue engineering

Q1 Computer Science

Bioprinting Pub Date : 2023-08-12 DOI:10.1016/j.bprint.2023.e00304

Saeed Ataollahi

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引用次数: 1

Abstract

Lattice structures are composed of interconnected porous unit cells that are arranged in a periodic and regular fashion. Their light wight and high specific strength alongside many other superior mechanical properties, have made them an excellent candidate for tissue engineering applications. In tissue engineering, porous structures (scaffolds) are employed for regeneration of living and healthy tissues and organs. Via their specific architecture, lattice structures can provide a proper environment for cells to attach to and colonize. Additive Manufacturing (AM) offers great flexibility in fabrication of lattice structures for tissue engineering. AM can apply complex design of unit cells and duplication patterns, to generate high quality lattice structures with good accuracy. In addition, biocompatibility and biodegradability of lattice structures that are main concerns in tissue engineering, can be addressed with a wide range of material choices in different AM methods. In this review, additive manufacturing of lattice structures in tissue engineering is discussed, with a focus on materials and AM methods that have been studied in the existing literature. Furthermore, various designs of unit cells in the AM of lattice structures, the effect of AM process parameters, challenges and future of this field are reviewed.

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组织工程中晶格结构的增材制造研究进展

点阵结构由相互连接的多孔单元组成，它们以周期性和规则的方式排列。它们的重量轻，比强度高，以及许多其他优越的机械性能，使它们成为组织工程应用的绝佳候选者。在组织工程中，多孔结构(支架)被用于再生活的和健康的组织和器官。通过其特定的结构，晶格结构可以为细胞附着和定植提供适当的环境。增材制造(AM)为组织工程中晶格结构的制造提供了极大的灵活性。增材制造可以应用复杂的单元格和重复图案设计，生成精度高的高质量晶格结构。此外，晶格结构的生物相容性和生物降解性是组织工程中主要关注的问题，可以通过不同的增材制造方法中广泛的材料选择来解决。本文讨论了组织工程中晶格结构的增材制造，重点介绍了现有文献中研究的材料和增材制造方法。此外，本文还介绍了点阵结构增材制造中单元胞的各种设计、增材制造工艺参数的影响以及该领域的挑战和发展前景。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bioprinting Computer Science-Computer Science Applications

CiteScore

11.50

自引率

0.00%

发文量

审稿时长

68 days

期刊介绍： Bioprinting is a broad-spectrum, multidisciplinary journal that covers all aspects of 3D fabrication technology involving biological tissues, organs and cells for medical and biotechnology applications. Topics covered include nanomaterials, biomaterials, scaffolds, 3D printing technology, imaging and CAD/CAM software and hardware, post-printing bioreactor maturation, cell and biological factor patterning, biofabrication, tissue engineering and other applications of 3D bioprinting technology. Bioprinting publishes research reports describing novel results with high clinical significance in all areas of 3D bioprinting research. Bioprinting issues contain a wide variety of review and analysis articles covering topics relevant to 3D bioprinting ranging from basic biological, material and technical advances to pre-clinical and clinical applications of 3D bioprinting.