{"title":"A review on additive manufacturing of lattice structures in tissue engineering","authors":"Saeed Ataollahi","doi":"10.1016/j.bprint.2023.e00304","DOIUrl":null,"url":null,"abstract":"<div><p><span>Lattice structures are composed of interconnected porous unit cells that are arranged in a periodic and regular fashion. Their light wight and high specific strength alongside many other superior </span>mechanical properties<span>, have made them an excellent candidate for tissue engineering<span><span> applications. In tissue engineering, porous structures<span> (scaffolds) are employed for regeneration of living and healthy tissues and organs. Via their specific architecture, lattice structures can provide a proper environment for cells to attach to and colonize. Additive Manufacturing<span> (AM) offers great flexibility in fabrication of lattice structures for tissue engineering. AM can apply complex design of unit cells and duplication patterns, to generate high quality lattice structures with good accuracy. In addition, biocompatibility and </span></span></span>biodegradability of lattice structures that are main concerns in tissue engineering, can be addressed with a wide range of material choices in different AM methods. In this review, additive manufacturing of lattice structures in tissue engineering is discussed, with a focus on materials and AM methods that have been studied in the existing literature. Furthermore, various designs of unit cells in the AM of lattice structures, the effect of AM process parameters, challenges and future of this field are reviewed.</span></span></p></div>","PeriodicalId":37770,"journal":{"name":"Bioprinting","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioprinting","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2405886623000477","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Computer Science","Score":null,"Total":0}
引用次数: 1
Abstract
Lattice structures are composed of interconnected porous unit cells that are arranged in a periodic and regular fashion. Their light wight and high specific strength alongside many other superior mechanical properties, have made them an excellent candidate for tissue engineering applications. In tissue engineering, porous structures (scaffolds) are employed for regeneration of living and healthy tissues and organs. Via their specific architecture, lattice structures can provide a proper environment for cells to attach to and colonize. Additive Manufacturing (AM) offers great flexibility in fabrication of lattice structures for tissue engineering. AM can apply complex design of unit cells and duplication patterns, to generate high quality lattice structures with good accuracy. In addition, biocompatibility and biodegradability of lattice structures that are main concerns in tissue engineering, can be addressed with a wide range of material choices in different AM methods. In this review, additive manufacturing of lattice structures in tissue engineering is discussed, with a focus on materials and AM methods that have been studied in the existing literature. Furthermore, various designs of unit cells in the AM of lattice structures, the effect of AM process parameters, challenges and future of this field are reviewed.
期刊介绍:
Bioprinting is a broad-spectrum, multidisciplinary journal that covers all aspects of 3D fabrication technology involving biological tissues, organs and cells for medical and biotechnology applications. Topics covered include nanomaterials, biomaterials, scaffolds, 3D printing technology, imaging and CAD/CAM software and hardware, post-printing bioreactor maturation, cell and biological factor patterning, biofabrication, tissue engineering and other applications of 3D bioprinting technology. Bioprinting publishes research reports describing novel results with high clinical significance in all areas of 3D bioprinting research. Bioprinting issues contain a wide variety of review and analysis articles covering topics relevant to 3D bioprinting ranging from basic biological, material and technical advances to pre-clinical and clinical applications of 3D bioprinting.