Wenlafaksyna XR, zastosowanie kliniczne większych dawek (> 150 mg)

Abstract

This paper discusses the dual serotonergic-noradrenergic mechanism of action of venlafaxine, its indications for use, and dosage. Special attention was paid to the clinical application of higher doses of the drug, above 150 mg in the treatment of depression and anxiety disorders. Venlafaxine is one of the most effective antidepressants. The maximum recommended dose is 225 mg/day for anxiety disorders and 375 mg/day for major depression. The use of higher doses of the drug allows to take full advantage of its dual mechanism of action and improve its effectiveness.