Brain structure and stroke risk score in subjects without a history of atrial fibrillation

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-05-13 DOI:10.1080/14017431.2022.2074094

M. Wykrętowicz, Łukasz Gąsiorowski, Anna Kłusek-Zielińska, K. Katulska

引用次数: 0

Abstract

Abstract CHA2DS2-VASc score system aids in clinical decision-making in subjects with atrial fibrillation (AF). Little is known on the association between CHA2DS2-VASc scores and brain structure in patients without cardiac arrhythmia. Detailed brain architecture analysis was performed. Assessment of bivariate correlation between the volume of segmented brain structures and Z-scores of CHA2DS2-VASc showed that higher risk scores correlated negatively and significantly with various brain framework. Our study confirms that a cluster of risk factors incorporated in a well-established risk score correlated with brain tissue volume independently of the presence of an arrhythmia.

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无房颤病史受试者的脑结构和卒中风险评分

CHA2DS2-VASc评分系统有助于房颤(AF)患者的临床决策。对于无心律失常患者CHA2DS2-VASc评分与脑结构之间的关系知之甚少。进行了详细的脑结构分析。对分节脑结构体积与CHA2DS2-VASc z -评分的双变量相关性评估显示，较高的风险评分与不同脑结构呈显著负相关。我们的研究证实，一组风险因素纳入了一个完善的风险评分，与脑组织体积相关，独立于心律失常的存在。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.