Survival benefit for pelvic trauma patients undergoing Resuscitative Endovascular Balloon Occlusion of the Aorta: Results of the AAST Aortic Occlusion for Resuscitation in Trauma Acute Care Surgery (AORTA) Registry

IF 2.4 3区 医学 Q3 CRITICAL CARE MEDICINE
John K. Bini , Claire Hardman , Jonathon Morrison , Thomas M. Scalea , Laura J. Moore , Jeanette M Podbielski , Kenji Inaba , Alice Piccinini , David S. Kauvar , Jeremey Cannon , Chance Spalding , Charles Fox , Ernest Moore , Joseph J. DuBose , The AAST AORTA Study Group
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引用次数: 9

Abstract

Background

Aortic occlusion (AO) to facilitate the acute resuscitation of trauma and acute care surgery patients in shock remains a controversial topic. Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) is an increasingly deployed method of AO. We hypothesized that in patients with non-compressible hemorrhage below the aortic bifurcation, the use of REBOA instead of open AO may be associated with a survival benefit.

Methods

From the AAST Aortic Occlusion for Resuscitation in Trauma and Acute Care Surgery (AORTA) registry, we identified 1494 patients requiring AO from 45 Level I and 4 Level II trauma centers. Presentation, intervention, and outcome variables were analyzed to compare REBOA vs open AO in patients with non-compressible hemorrhage below the aortic bifurcation.

Results

From December 2014 to January 2019, 217 patients with Zone 3 REBOA or Open AO who required pelvic packing, pelvic fixation or pelvic angio-embolization were identified. Of these, 109 AO patients had injuries isolated to below the aortic bifurcation (REBOA, 84; open AO, 25). Patients with intra-abdominal or thoracic sources of bleeding, above deployment Zone 3 were excluded. Overall mortality was lower in the REBOA group (35.% vs 80%, p <.001). Excluding patients who arrived with CPR in progress, the REBOA group had lower mortality (33.33% vs. 68.75%, p = 0.012). Of the survivors, systemic complications were not significantly different between groups. In the REBOA group, 16 patients had complications secondary to vascular access. Intensive care lengths of stay and ventilator days were both significantly shorter in REBOA patients who survived to discharge.

Conclusions

This study compared outcomes for patients with hemorrhage below the aortic bifurcation treated with REBOA to those treated with open AO. Survival was significantly higher in REBOA patients compared to open AO patients, while complications in survivors were not different. Given the higher survival in REBOA patients, we conclude that REBOA should be used for patients with hemorrhagic shock secondary to pelvic trauma instead of open AO.

Level III Evidence

Therapeutic

盆腔创伤患者接受复苏血管内球囊阻断主动脉的生存益处:AAST创伤急性护理外科(Aorta)登记中主动脉阻断复苏的结果。
背景:主动脉闭塞术(AO)促进创伤和休克外科患者的急性复苏仍然是一个有争议的话题。复苏血管内球囊阻断主动脉(REBOA)是一种越来越广泛应用的AO方法。我们假设在主动脉分叉以下不可压缩性出血的患者中,使用REBOA而不是开放AO可能与生存获益相关。方法从AAST创伤和急性护理外科(AORTA)主动脉闭塞复苏登记中,我们确定了来自45个一级和4个二级创伤中心的1494例需要AO的患者。分析表现、干预和结果变量,比较REBOA和开放AO在主动脉分叉以下不可压缩性出血患者中的应用。结果2014年12月至2019年1月,217例3区REBOA或Open AO患者需要盆腔填充物、盆腔固定或盆腔血管栓塞。其中,109例AO患者的损伤位于主动脉分叉以下(REBOA, 84;open AO, 25)。排除腹腔或胸腔内出血源及部署区3以上的患者。REBOA组的总死亡率较低(35。% vs 80%, p <.001)。排除正在进行心肺复苏的患者,REBOA组的死亡率较低(33.33%比68.75%,p = 0.012)。在幸存者中,两组之间的系统性并发症无显著差异。在REBOA组中,16例患者出现继发于血管通路的并发症。存活至出院的REBOA患者重症监护时间和呼吸机天数均显著缩短。结论:本研究比较了REBOA和开放式AO治疗主动脉分叉下出血患者的预后。REBOA患者的生存率明显高于开放AO患者,而幸存者的并发症没有差异。考虑到REBOA患者较高的生存率,我们认为REBOA应该用于盆腔创伤继发性失血性休克患者,而不是开放性AO。III级证据治疗性
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来源期刊
CiteScore
4.00
自引率
8.00%
发文量
699
审稿时长
96 days
期刊介绍: Injury was founded in 1969 and is an international journal dealing with all aspects of trauma care and accident surgery. Our primary aim is to facilitate the exchange of ideas, techniques and information among all members of the trauma team.
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