Inactivation of sars-cov-2 by povidone-iodine products: Implications for effective mouth rinsing and gargling

IF 0.4 4区农林科学 Q4 VETERINARY SCIENCES

Japanese Journal of Veterinary Research Pub Date : 2021-08-01 DOI:10.14943/jjvr.69.3.183

H. Kariwa, H. Sawa, Shintaro Kobayashi

引用次数: 4

Abstract

Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 is transmitted mainly via droplets and contact. The implementation of infection control measures is important to reduce the number of COVID-19 cases. Thus, the ability of several povidone-iodine (PVP-I) products to inactivate SARS-CoV-2 was evaluated based on their in vitro inactivation efficacy. PVP-I solutions such as Isodine Gargle® (ethical and consumer products), Isodine Gargle C®, and Isodine Nodo Fresh® for 30 or 60 s decreased the viral infectivity level from 2-4 × 106 TCID50/ml to below the detectable level (> 99.9% reduction). Our results indicate that the use of Isodine® mouthwash and gargle products is an effective infection control measure against SARS-CoV-2.

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聚维酮碘产品灭活sars-cov-2:对有效漱口和漱口的影响

2019冠状病毒病（新冠肺炎）是由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起的。严重急性呼吸系统综合征冠状病毒2型主要通过飞沫和接触传播。实施感染控制措施对于减少新冠肺炎病例数量至关重要。因此，基于几种聚维酮碘（PVP-I）产品的体外灭活效力，评估了其灭活严重急性呼吸系统综合征冠状病毒2型的能力。PVP-I溶液，如Isodine Gargle®（伦理和消费品）、Isodine Gargle C®和Isodine Nodo Fresh®，持续30或60秒，将病毒感染水平从2-4×106 TCID50/ml降低到可检测水平以下（降低>99.9%）。我们的研究结果表明，使用Isodine®漱口水和漱口产品是对抗严重急性呼吸系统综合征冠状病毒2型的有效感染控制措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Japanese Journal of Veterinary Research 农林科学-兽医学

CiteScore

1.00

自引率

0.00%

发文量

审稿时长

>36 weeks

期刊介绍： The Japanese Journal of Veterinary Research (JJVR) quarterly publishes peer-reviewed articles on all aspects of veterinary science. JJVR was originally published as a “University Journal” of veterinary science at Hokkaido University from more than 60 years ago. Currently, JJVR, is Japan’s leading scientific veterinary journal, and provides valuable information for the development of veterinary science by welcoming contributions from researchers worldwide. JJVR offers online submission for Regular Papers, Short Communications, and Review Articles that are unpublished and not being considered for publication elsewhere. Research areas include: Anatomy, Physiology, Biochemistry, Pharmacology, Microbiology, Infectious diseases, Parasitology, Laboratory Animal Science and Medicine, Internal Medicine, Surgery, Pathology, Theriogenology, Molecular Medicine, Public Health, Radiation Biology, Toxicology, Wildlife Biology and Medicine, Veterinary Hygiene, The other fields related to veterinary science.