Risk Factors of Postpartum Cardiovascular Disease in Patients with Gestational Diabetes Mellitus

W. Liu, Jing Wang, Hongli Wu, Yuxiang Hang, Lingling Gong
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Abstract

Objective: To investigate the risk factors of postpartum cardiovascular disease in patients with gestational diabetes mellitus (GDM). Methods: From December 2020 to December 2021, pregnant women who underwent 75-g oral glucose tolerance test (OGTT) between 24 and 28 weeks of gestation and were diagnosed with GDM were selected as the research subjects. These women were followed-up after delivery. Results: The average fasting plasma glucose (FPG) levels of these women were 6.25 ± 1.36 mmol/L before discharge and 5.01 ± 1.45 mmol/L at 42 days after delivery; the average 2-hour plasma glucose (2hPG) levels were 11.23 ± 2.01 mmol/L before discharge and 7.98 ± 1.23 mmol/L at 42 days after delivery; the average insulin levels were 8.36 ± 1.98 mmol/L before discharge and 2.98 ± 1.36 mmol/L at 42 days after delivery. There were 46 patients with postpartum cardiovascular disease, with an incidence rate of 22.89%. Conclusion: By improving the postpartum management of patients, the weight of GDM patients can be better controlled, their insulin sensitivity can be increased, and the occurrence of glucose and lipid metabolism disorders can be reduced.
妊娠期糖尿病患者产后心血管疾病的危险因素
目的:探讨妊娠期糖尿病(GDM)患者产后心血管疾病的危险因素。方法:从2020年12月至2021年12月,选择在妊娠24-28周期间接受75-g口服葡萄糖耐量试验(OGTT)并被诊断为GDM的孕妇作为研究对象。这些妇女在分娩后接受了随访。结果:这些妇女的平均空腹血糖(FPG)水平在出院前为6.25±1.36mmol/L,在产后42天为5.01±1.45mmol/L;出院前平均2小时血糖(2hPG)为11.23±2.01 mmol/L,产后42天平均为7.98±1.23 mmol/L;出院前平均胰岛素水平为8.36±1.98mmol/L,产后42天平均胰岛素水平2.98±1.36mmol/L。产后心血管疾病46例,发病率22.89%。结论:通过改进患者的产后管理,可以更好地控制GDM患者的体重,提高其胰岛素敏感性,减少糖脂代谢紊乱的发生。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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