Cáncer palatosinusal t4a/b: extensión de las resecciones oncológicas

David O. Simkin, Hugo A. Pardo, Alejandro Rubino, Osvaldo González Aguilar, Gastón Omeñuk, María Montserrat Pujadas Bigi
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Abstract

Background: the problems of reconstructive surgery for the midface are variable and can be very complex. The anatomical proximity of the midface to the orbit, base of the skull and maxillary sinuses is a challenge for the surgeon who must perform a curative resection. Objective: The aim of this presentation is to report the survival rate and disease-free interval in T4a and T4b neoplasms of the palate and paranasal sinuses consecutively resected over a 30-year period. Material and methods: Surgery was extended to the orbit in 85.2%, the skull in 8.3%, the neck in 18.7% and the parotid gland in 7.3%. Soft tissue reconstruction was performed using free flaps in 32.5%, muscle flaps in 21.6%, local flaps in 20.2%, musculocutaneous flaps in 14.7% and skin flaps in 11.3%. Results: Local and general complications were reported, and 4/203 patients (2%) died. At 5 years, overall survival was 62.5% and disease-free survival was 53%. Univariate analysis revealed that lack of previous treatment was significantly associated with recurrence and squamous cell carcinoma was a predictor of survival. Conclusions: The indication of exenteration is mandatory in the presence of ophthalmoplegia or involvement of the orbital content. Survival at 5 years is acceptable, considering the advanced stages of the disease. In some patients, previous treatments were
腭咽癌t4a/b:肿瘤切除的扩展
背景:面中部重建手术的问题是多变的,可能非常复杂。面中部与眼眶、颅底和上颌窦的解剖接近程度对必须进行根治性切除的外科医生来说是一个挑战。目的:本报告旨在报告30年内连续切除的T4a和T4b腭鼻窦肿瘤的生存率和无病间隔。材料和方法:手术扩展至眼眶85.2%,颅骨8.3%,颈部18.7%,腮腺7.3%。软组织重建采用游离皮瓣32.5%,肌肉皮瓣21.6%,局部皮瓣20.2%,肌肉皮片14.7%,皮片11.3%。结果:报告了局部和全身并发症,4/203例患者(2%)死亡。5年时,总生存率为62.5%,无病生存率为53%。单因素分析显示,缺乏既往治疗与复发显著相关,鳞状细胞癌是生存的预测因素。结论:在存在眼肌麻痹或眼眶内容物受累的情况下,必须进行清眼术。考虑到疾病的晚期,5年的生存期是可以接受的。在一些患者中,以前的治疗是
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