Effect of Probiotics on Rotavirus and Non-Rotavirus Diarrhea in Infants: Randomized Controlled Trial

Esculapio Pub Date : 2022-03-01 DOI:10.51273/esc22.251831

Fariha Ahmad Khan, Zoobia Irum, Muhammad Zeeshan Khan, Neelofar Yousaf, Mariyam Iftikhar Piracha, Sarah Zaheer

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Abstract

Objective: In this trial, we have observed efficacy of two different probiotics in Rotavirus and non-Rotavirus diarrhea in infants of 6 months to 12 months. Method: The study was done to observe efficacy of two different probiotic strains in Rotavirus and non- Rotavirus diarrhea in infants. The study included the infants suffering from acute severe diarrhea. 105 infants were selected and they were divided randomly into three groups. There were 35 infants in one group. The samples of stool were sent to microbiology lab for Rotavirus testing. The treatment plan was standard treatment of diarrhea for infants in group A. The treatment plan for infants of group B and group C included same standard management of diarrhea, in addition they also received probiotics Enterococcus faecium SF68 and Saccharomyces boulardii respectively. Results: There was reduction in stool output and improvement in consistency of stool in infants of group B and C as compared to infants of group A. There was decrease in stool frequency in non-Rotavirus diarrhea in infants of group B and C while there was no significant difference between groups regarding Rotavirus diarrhea. Conclusion: Probiotics helped to decrease the stool output in non-Rotavirus diarrhea. There was not any significant difference in groups regarding Rotavirus diarrhea. How to cite: Khan FA, Irum z, Khan MZ, Yousaf N, Piracha MI, Zaheer S. Effect of Probiotics on Rotavirus and Non- Rotavirus Diarrhea in Infants: Randomized Controlled Trial. Esculapio - JSIMS 2022;18(03):248-252 Keywords: Rotavirus, Non-Rotavirus, Saccharomyces boulardii,, Enterococcus faecium Sf68

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益生菌对婴幼儿轮状病毒和非轮状病毒腹泻的影响:随机对照试验

目的：在本试验中，我们观察了两种不同益生菌对6个月至12个月婴儿轮状病毒和非轮状病毒腹泻的疗效。方法：观察两种不同益生菌菌株对婴幼儿轮状病毒和非轮状病毒腹泻的疗效。这项研究包括患有急性严重腹泻的婴儿。105名婴儿被随机分为三组。一组有35名婴儿。粪便样本被送往微生物实验室进行轮状病毒检测。治疗方案为A组婴儿腹泻的标准治疗。B组和C组婴儿的治疗方案包括相同的腹泻标准治疗，此外，他们还分别接受了益生菌粪肠球菌SF68和布拉酵母。结果：与A组婴儿相比，B组和C组婴儿的大便量减少，大便稠度改善。B组和C组婴儿非轮状病毒性腹泻的大便频率降低，而轮状病毒腹泻在两组之间没有显著差异。结论：益生菌有助于降低非轮状病毒性腹泻患者的排便量。在轮状病毒腹泻方面，各组之间没有任何显著差异。如何引用：Khan FA，Irum z，Khan MZ，Yousaf N，Piracha MI，Zaheer S.益生菌对婴儿轮状病毒和非轮状病毒腹泻的影响：随机对照试验。埃斯库拉皮奥-JSIMS 2022；18（03）：248-252关键词：轮状病毒非轮状病毒布拉酵母粪肠球菌Sf68

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Esculapio

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12 weeks