Novel easy-to-use approach to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA-carrying extracellular vesicles in plasma

Abstract

The difficult times of the coronavirus disease 2019 (COVID-19) pandemic have necessitated the rapid development of sensitive diagnostic tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. According to clinical practice guided by World Health Organization (WHO), Centers for Disease Control and Prevention (CDC), European Centre for Disease Prevention and Control (ECDC), and related global health institutions, the selection of SARS-CoV-2 test should be based on the wider context including both the prevalence of the virus variants in the population and the status of the tested individual.