Chiral membranes for enantiomer separation: A comprehensive review

IF 9 1区工程技术 Q1 ENGINEERING, CHEMICAL

Separation and Purification Technology Pub Date : 2022-07-01 DOI:10.1016/j.seppur.2022.121034

Qingsong Cheng, Qian Ma, Hebing Pei, Zunli Mo

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引用次数: 16

Abstract

Chirality is a basic property of nature. Chiral compounds are widely used in medicine. The pharmacological action of enantiomers in human body varies widely or even opposites. Therefore, the purity of chiral compounds plays an important role in human health and safety. Enantiomer separation is a necessary process to obtain pure chiral compounds. How to efficiently separate enantiomers has been a hot research topic in the world. Chiral membrane separation has many advantages and has great potential in enantiomer separation. The key to chiral membrane separation is the development of membrane materials. At present, many promising new materials have emerged in the field of chiral membrane separation. Unfortunately, systematic reviews of chiral membrane separation are few and far between due to the wide range of disciplines involved. Therefore, Based on chiral membrane materials and starting from the mechanism of chiral membrane separation, this paper systematically describes the research progress in the chiral separation of graphene material membrane, metal–organic framework membrane and polymer membrane. In addition, the challenges and prospects of chiral membrane separation are analyzed. It is hoped that it can be helpful for the further study of chiral membrane separation.

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对映体分离的手性膜:综述

手性是自然界的基本性质。手性化合物在医学上有广泛的应用。对映体在人体内的药理作用差异很大，甚至相反。因此，手性化合物的纯度对人体健康和安全起着重要的作用。对映体分离是获得纯手性化合物的必要过程。如何高效分离对映体一直是国内外研究的热点。手性膜分离具有许多优点，在对映体分离中具有很大的潜力。手性膜分离的关键是膜材料的发展。目前，手性膜分离领域出现了许多有前途的新材料。不幸的是，由于涉及的学科范围广泛，对手性膜分离的系统综述很少。因此，本文以手性膜材料为基础，从手性膜分离机理出发，系统介绍了石墨烯材料膜、金属有机骨架膜和高分子膜的手性分离研究进展。此外，还分析了手性膜分离技术面临的挑战和发展前景。希望能对手性膜分离的进一步研究有所帮助。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Separation and Purification Technology 工程技术-工程：化工

CiteScore

14.00

自引率

12.80%

发文量

2347

审稿时长

43 days

期刊介绍： Separation and Purification Technology is a premier journal committed to sharing innovative methods for separation and purification in chemical and environmental engineering, encompassing both homogeneous solutions and heterogeneous mixtures. Our scope includes the separation and/or purification of liquids, vapors, and gases, as well as carbon capture and separation techniques. However, it's important to note that methods solely intended for analytical purposes are not within the scope of the journal. Additionally, disciplines such as soil science, polymer science, and metallurgy fall outside the purview of Separation and Purification Technology. Join us in advancing the field of separation and purification methods for sustainable solutions in chemical and environmental engineering.