Delayed Appearance of Klein-Levin Syndrome Caused by Traumatic Brain Injury: A Case Report

Ali Javadpour, S. Yaghmaei, Nejla Mostafeenezhad, N. Derakhshan, P. Schofield
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Abstract

Background: The combination of hypersomnia and any of: hyper-phagia, hyper-sexuality, or mood changes is known as Klein-Levin Syndrome. This syndrome is quite infrequent and mostly restricted to adolescent males. Case Description: A young patient with KLS is presented in this report. He was presented with relapsing-remitting hypersomnia and irritability more than two years after incurring a traumatic brain injury. Magnetic resonance imaging (MRI) showed hyperintensity in the posterolateral part of the right temporal region, matched with the brain injuries caused by the old trauma. His extremely long sleep episodes forced medical team to provide him with some necessary basic cares such as nasogastric tube and urinary catheter. Five consecutive weeks of taking modafinil got his sleep pattern back to normal. Conclusion: In addition to medical treatment which is inevitable for severe cases, family and social support is extremely vital for managing KLS patients.
外伤性脑损伤致Klein-Levin综合征延迟表现1例报告
背景:嗜睡和任何一种:嗜食、性欲亢进或情绪变化的结合被称为Klein-Levin综合征。这种综合症并不常见,而且主要局限于青春期男性。病例描述:在这个报告中提出了一个年轻的KLS患者。他在遭受创伤性脑损伤两年多后出现复发缓解型嗜睡和易怒。磁共振成像(MRI)显示右侧颞区后外侧高强度,与旧伤所致脑损伤相符。他的睡眠时间特别长,迫使医疗小组为他提供一些必要的基本护理,如鼻胃管和导尿管。连续五周服用莫达非尼使他的睡眠模式恢复正常。结论:除了重症患者不可避免的药物治疗外,家庭和社会支持对治疗KLS患者至关重要。
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