Systemic sclerosis-associated interstitial lung disease: Diagnostic approaches and challenges

Q3 Health Professions

Revista Colombiana de Reumatologia Pub Date : 2024-04-01 DOI:10.1016/j.rcreu.2023.07.001

Jessica L. Fairley , Nicole S.L. Goh , Mandana Nikpour

引用次数: 0

Abstract

Interstitial lung disease (ILD) is a leading cause of both morbidity and mortality in systemic sclerosis (SSc). Radiographic lung abnormalities on high-resolution computed tomography (HRCT) imaging may be identified in 75–90% of those with SSc, while clinically significant ILD occurs in up to 40%. Early detection is important as early treatment in those with progressive ILD may improve outcomes. Appropriately risk-stratifying systemic sclerosis-associated ILD (SSc-ILD) is important in identifying those at highest risk of progression. This article summarises recent advances in SSc-ILD, particularly recommendations for screening, defining disease progression and monitoring.

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系统性硬化相关间质性肺病：诊断方法和挑战

间质性肺病（ILD）是系统性硬化症（SSc）患者发病和死亡的主要原因。75%-90%的系统性硬化症患者可通过高分辨率计算机断层扫描（HRCT）成像发现肺部影像学异常，而多达 40% 的患者会出现有临床意义的 ILD。早期发现非常重要，因为对进展性 ILD 患者进行早期治疗可改善预后。对系统性硬化症相关性 ILD（SSc-ILD）进行适当的风险分级对于识别进展风险最高的患者非常重要。本文总结了 SSc-ILD 的最新进展，尤其是筛查、疾病进展定义和监测方面的建议。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista Colombiana de Reumatologia Medicine-Rheumatology

CiteScore

0.80

自引率

0.00%

发文量

期刊介绍： The Colombian Journal of Rheumatology (Revista Colombiana de Reumatología) is the official organ of the Colombian Association of Rheumatology (Asociación Colombiana de Reumatología) and the Central American, Caribbean and Andean Association of Rheumatology (Asociación Centroamericana Caribe Andina de Reumatología) - ACCA. It was created in December 1993 with the purpose of disseminating scientific information derived from primary and secondary research and presenting cases coming from the practice of Rheumatology in Latin America. Since its foundation, the Journal has been characterized by its plurality with subjects of all rheumatic and osteomuscular pathologies, in the form of original articles, historical articles, economic evaluations, and articles of reflection and education in Medicine. It covers an extensive area of topics ranging from the broad spectrum of the clinical aspects of rheumatology and related areas in autoimmunity (both in pediatric and adult pathologies), to aspects of basic sciences. It is an academic tool for the different members of the academic and scientific community at their different levels of training, from undergraduate to post-doctoral degrees, managing to integrate all actors inter and trans disciplinarily. It is intended for rheumatologists, general internists, specialists in related areas, and general practitioners in the country and abroad. It has become an important space in the work of all rheumatologists from Central and South America.