From the Editor

Q2 Social Sciences
J. Poe
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引用次数: 0

Abstract

The prion diseases are a group of neuro- degenerative conditions affecting both humans and animals. They are transmissible after inoculation, have long incubation periods, and have been known as the spongiform encephalopathies, slow virus diseases, or transmissible dementias. The human diseases include Creutzfeldt-Jakob disease (CJD), Gerstmann-Straussler- Scheinker disease (GSS), and kuru. All are associated with the deposition in the brain of an abnormal, partially protease resistant, isoform of a host encoded protein, the prion protein (PrP). An impressive body of exper- imental evidence now argues persuasively that this abnormal isoform of PrP central and conceivably component of transmissible agent types coding mutations diagnosis
来自编辑器
朊病毒疾病是一组影响人类和动物的神经退行性疾病。它们在接种后具有传播性,潜伏期长,被称为海绵状脑病、慢病毒性疾病或传播性痴呆。人类疾病包括克雅氏病(CJD)、格氏-斯特劳斯勒-谢因克病(GSS)和库鲁病。所有这些都与宿主编码的蛋白质朊病毒蛋白(PrP)的异常、部分蛋白酶抗性的同种型在大脑中的沉积有关。一组令人印象深刻的实验证据现在令人信服地证明,这种PrP的异常亚型是编码突变诊断的可传播因子类型的中心和可想象的组成部分
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来源期刊
Journal of Library and Information Services in Distance Learning
Journal of Library and Information Services in Distance Learning Social Sciences-Library and Information Sciences
CiteScore
1.90
自引率
0.00%
发文量
15
期刊介绍: The Journal of Library & Information Services in Distance Learning is the first journal to specifically address the issues and concerns of librarians and information specialists in the rapidly growing field of distance education. The issues surrounding the delivery of library services to this population are sufficiently unique so as to require the specialty supplied by this journal. The journal accepts original research, theoretical papers, substantive articles, essays, book and literature reviews, and research reports that cover programs and innovations throughout the international community.
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