The Study Around Effects Cell Wall of Streptococcus pyogenes on the Immune System Response

Abstract

Many of the most common diseases aff ecting humans are caused by Streptococcus. The study of the cell wall of these bacteria is directly related to the immune response. In our study, about 20 throat swabs were collected for children aged 5 to 15 years, according to the procedures and protocol of the World Health Organization (WHO), to search for Streptococcus pyogenes. We cultured bacteria on blood agar media and then used HA and HAI to obtain the main component of the bacteria wall, peptidoglycan, to determine its immune response. Whereas the study we carried out proved that the injection of Ags S/C after one month and collecting serum from these labs gives titers in group 1 1:1280 and in group 2 1:640, indicating that antigens are highly virulence (complex antigens), composed of peptides and carbohydrates. All samples we tested gave positive results and generated an immune response to the bacteria’s cell wall peptidoglycan material