Zhonggao Zhou , Jing Li , Yue Wu , Yangyang Yuan , Lingfang Kong , Jun Xue , Zhiqiang Huang
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引用次数: 6
Abstract
Chiral ionic liquids (CILs) are widely used solvents and materials with prominent properties. Carbohydrate-derived imidazolium-based CILs represent a distinctive type of CILs possessing multiple chiral centers from natural chiral pool. Herein, a series of glucopyranoside-substituted imidazolium-based CILs (Glu-imi-CILs) were synthesized and evaluated as ligands for Pd-catalyzed homo-coupling reactions of arylboronic acids in water. The glucopyranoside substituent was instrumental for improving the catalytic activity of the resulting catalysts. Moreover, a Glu-imi-CIL with a free hydroxyl group for additional coordination was found to be the most efficient ligand. A series of symmetric biaryl compounds (13 examples) were synthesized from arylboronic acids by this method in high isolated yields (85−99%).
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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