Silent Somatotropic Adenoma and Pregnancy: About A Case

Abstract

Somatotropic adenomas are classically a source of hypersecretion of growth hormone (GH) and consequently of insulin growth factor 1 (IGF1) and responsible of the clinical signs of acromegaly. Rarely, these adenomas remain “silent”, without any obvious clinical manifestation. They can then be screened on the basis of a systematic assay of growth hormone under oral glucose tolerance test (GH/ OGTT) and IGF1 or can be diagnosed only in the immunohistochemical study as in the case of a patient we report and the evolution of her disease during pregnancy.