Helicobacter Pylori and Epstein-Barr Virus Co-Infection in Polish Patients with Gastric Cancer – a Pilot Study

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Applied Bio Materials Pub Date : 2022-02-27 DOI:10.33073/pjm-2022-004

M. Dzikowiec, Przemysław Lik, J. Kiszałkiewicz, A. Kuczyńska, Marek Mordalski, D. Nejc, J. Piekarski, E. Brzeziańska-Lasota, D. Pastuszak-Lewandoska

引用次数: 1

Abstract

Abstract The infectious agents may be the etiological factor of up to 15–20% of cancers. In stomach cancer, attention is paid to Helicobacter pylori and Epstein-Barr virus, both of which cause gastritis and can lead to tumor development. In co-infection, the inflammatory process is much more intense. We assessed the seroprevalence towards H. pylori and EBV in 32 patients with diagnosed gastric cancer. H. pylori antibodies were found in 69% patients, and anti-EBV – in all of them. The study confirmed that co-infection of H. pylori and EBV seems to be important in etiopathology of gastric cancer.

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波兰癌症患者幽门螺杆菌和EB病毒共感染的初步研究

感染因子可能是高达15-20%癌症的病因。在胃癌中，人们关注的是幽门螺杆菌和爱泼斯坦-巴尔病毒，这两种病毒都会引起胃炎并导致肿瘤发展。在合并感染中，炎症过程更加强烈。我们评估了32例胃癌患者幽门螺杆菌和EBV的血清患病率。69%的患者有幽门螺杆菌抗体，所有患者均有ebv抗体。本研究证实幽门螺杆菌和EBV的联合感染在胃癌的发病过程中起重要作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464