Dobutamine Stress Echocardiography in Chronic Kidney Disease Patients Candidates for Renal Transplantation

IF 2.2 4区计算机科学 Q3 COMPUTER SCIENCE, INFORMATION SYSTEMS

ACM Sigcomm Computer Communication Review Pub Date : 2020-09-23 DOI:10.11648/J.CCR.20200403.22

Abdel Mohsen Mostafa Aboualia

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Abstract

Background: Dobutamine stress echocardiography (DSE) is used for induction of ischemia in different population. One of those is chronic kidney disease patients before renal transplantation for pre-operative risk assessment. Aim of the work: to evaluate the difference in dobutamine stress echocardiography between those with chronic kidney disease (CKD) on regular dialysis and patient with no known history of chronic renal impairment. Methods: From February 2016 to January 2017, twenty consecutive chronic kidney disease patients prepared for renal transplantation without history suggestive of ischemic heart disease and 40 consecutive patients with without history of renal impairment. Their heart rate, dobutamine dose, atropine dose and adverse side effects were compared between the two groups. Results: Both groups were matched in age and risk factors. Peak heart rate (HR) (133.7±16.99 vs. 144.08±10.99 b/m, P=0.012), time to target heart rate was (17.75±3.29 vs. 13.05±2.95 min, p=0.001) and dobutamine and atropine doses were higher in chronic kidney disease group than other group. Adverse reactions present in both groups but more incidence in CKD group. Conclusion: Chronic kidney disease patients response to dobutamine when underwent dobutamine stress echocardiography showed delayed effect of it with more dobutamine and atropine doses needed and more adverse reactions including Bezold-Jarisch reflex.

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多巴酚丁胺应激超声心动图在慢性肾病肾移植患者中的应用

背景：多巴酚丁胺负荷超声心动图（DSE）用于不同人群的缺血诱导。其中之一是肾移植前进行术前风险评估的慢性肾脏病患者。工作目的：评估定期透析的慢性肾脏疾病（CKD）患者和无慢性肾功能损害史的患者在多巴酚丁胺负荷超声心动图中的差异。方法：自2016年2月至2017年1月，连续20名慢性肾脏病患者准备接受肾移植，无缺血性心脏病病史，连续40名患者无肾损伤病史。比较两组患者的心率、多巴酚丁胺剂量、阿托品剂量及不良反应。结果：两组患者的年龄和危险因素相匹配。峰值心率（HR）（133.7±16.99 vs.144.08±10.99 b/m，P=0.012），达到目标心率的时间（17.75±3.29 vs.13.05±2.95分钟，P=0.001），多巴酚丁胺和阿托品剂量在慢性肾病组高于其他组。两组均存在不良反应，但CKD组发生率更高。结论：慢性肾脏病患者在接受多巴酚丁胺负荷超声心动图检查时对多巴酚胺的反应显示其延迟作用，需要更多的多巴酚明和阿托品剂量，以及更多的不良反应，包括Bezold-Jarisch反射。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACM Sigcomm Computer Communication Review 工程技术-计算机：信息系统

CiteScore

6.90

自引率

3.60%

发文量

审稿时长

4-8 weeks

期刊介绍： Computer Communication Review (CCR) is an online publication of the ACM Special Interest Group on Data Communication (SIGCOMM) and publishes articles on topics within the SIG''s field of interest. Technical papers accepted to CCR typically report on practical advances or the practical applications of theoretical advances. CCR serves as a forum for interesting and novel ideas at an early stage in their development. The focus is on timely dissemination of new ideas that may help trigger additional investigations. While the innovation and timeliness are the major criteria for its acceptance, technical robustness and readability will also be considered in the review process. We particularly encourage papers with early evaluation or feasibility studies.