Possibilities of pain management during photodynamic therapy

Q3 Medicine
S. Shinkarev, V. Borisov, S. N. Boldyrev, V. Podolsky, Z. I. Abdurashidov, A. P. Zagadaev, O. N. Klycheva
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引用次数: 0

Abstract

The authors consider the possibilities of pain management during photodynamic therapy (PDT) of visible tumors based on the observation of 102 patients. Of the total number of patients, 62 had verified basal cell skin cancer, 10 people - squamous cell skin cancer, another 10 - oral and oropharynx mucosa cancer, 8 - oral leukoplakia and dysplasia, in 6 - lower lip cancer, in 4 - breast cancer, in 2 - other localizations of neoplasms. In 15 patients, nonsteroidal anti-inflammatory drugs (NSAID) were used as pain management, in 69 - a combination of NSAID with tramadol, in 14 - nerve block anesthesia, in 4 - PDT was performed under general anesthesia. The intensity of pain syndrome during laser irradiation of the tumor was assessed on the verbal rating scale (VRS). The absence of pain was recorded in 9% of cases. Mild pain was noted by 58% of patients, moderate pain - 20%, severe pain - 10%, very severe pain was noted by 3% of patients. The degree of expression of pain syndrome during PDT depends on the incidence of a lesion, histological form of tumor, and method of anesthesia. NSAID alone, or in combination with an opioid analgesic, allows effective control of pain syndrome in PDT of basal cell skin cancer in 89%, in PDT of squamous cell skin cancer in 66% of observations. Nerve block anesthesia allows stoping pain syndrome during PDT of oropharyngeal tumors.
光动力治疗中疼痛管理的可能性
作者通过对102例可见肿瘤光动力治疗(PDT)患者的观察,探讨了疼痛管理的可能性。在所有患者中,62人确诊为基底细胞皮肤癌,10人确诊为鳞状细胞皮肤癌,10人确诊为口腔和口咽粘膜癌,8人确诊为口腔白斑和发育不良,6人确诊为下唇癌,4人确诊为乳腺癌,2人确诊为其他肿瘤。15例患者采用非甾体抗炎药(NSAID)止痛,69例患者采用非甾体抗炎药联合曲马多止痛,14例患者采用神经阻滞麻醉,4例患者在全麻下行PDT。采用口头评定量表(VRS)评估肿瘤激光照射时疼痛综合征的强度。9%的病例无疼痛。58%的患者感到轻微疼痛,20%的患者感到中度疼痛,10%的患者感到严重疼痛,3%的患者感到非常严重的疼痛。PDT期间疼痛综合征的表达程度取决于病变的发生率、肿瘤的组织学形式和麻醉方法。单独使用非甾体抗炎药,或与阿片类镇痛药联合使用,可以有效控制89%的基底细胞皮肤癌PDT患者的疼痛综合征,66%的鳞状细胞皮肤癌PDT患者的疼痛综合征。神经阻滞麻醉可以阻止口咽肿瘤PDT期间的疼痛综合征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biomedical Photonics
Biomedical Photonics Medicine-Surgery
CiteScore
1.80
自引率
0.00%
发文量
19
审稿时长
8 weeks
期刊介绍: The main goal of the journal – to promote the development of Russian biomedical photonics and implementation of its advances into medical practice. The primary objectives: - Presentation of up-to-date results of scientific and in research and scientific and practical (clinical and experimental) activity in the field of biomedical photonics. - Development of united Russian media for integration of knowledge and experience of scientists and practitioners in this field. - Distribution of best practices in laser medicine to regions. - Keeping the clinicians informed about new methods and devices for laser medicine - Approval of investigations of Ph.D candidates and applicants.
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