Laís Rosa Viana, Anna Caroline Perina Luiz, Bianca Cristine Favero-Santos, Carla de Moraes Salgado, Maria Cristina Cintra Gomes-Marcondes
{"title":"Leucine-rich diet minimises liver glycogen mobilisation and modulates liver gluconeogenesis enzyme expression in tumour-bearing cachectic rats","authors":"Laís Rosa Viana, Anna Caroline Perina Luiz, Bianca Cristine Favero-Santos, Carla de Moraes Salgado, Maria Cristina Cintra Gomes-Marcondes","doi":"10.1002/j.2617-1619.2018.tb00003.x","DOIUrl":null,"url":null,"abstract":"Cachexia is defined as a complex metabolic syndrome that is associated with tissue damage. Some studies have shown that the liver metabolic alterations contribute to overall host tissue wasting. Knowing that leucine acts as cell signalling, we evaluated hepatic metabolism in Walker 256 tumour‐bearing rats and investigated the modulatory effects of a leucine‐rich diet.","PeriodicalId":73544,"journal":{"name":"JCSM rapid communications","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2018-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/j.2617-1619.2018.tb00003.x","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JCSM rapid communications","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/j.2617-1619.2018.tb00003.x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
Cachexia is defined as a complex metabolic syndrome that is associated with tissue damage. Some studies have shown that the liver metabolic alterations contribute to overall host tissue wasting. Knowing that leucine acts as cell signalling, we evaluated hepatic metabolism in Walker 256 tumour‐bearing rats and investigated the modulatory effects of a leucine‐rich diet.
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