Ethnomedicinal uses, phytochemistry, pharmacological properties and toxicology of Curcuma caesia Roxb.: a review

IF 1.8 Q3 PHARMACOLOGY & PHARMACY

Advances in Traditional Medicine Pub Date : 2022-08-13 DOI:10.1007/s13596-022-00658-y

Zainol Haida, Jaafar Juju Nakasha, Uma Rani Sinniah, Mansor Hakiman

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引用次数: 1

Abstract

Curcuma caesia or commonly known as black turmeric is belongs to family Zingiberaceae. The rhizome which is the most important part of this species is widely used as a folk medicine for the treatment of asthma, fever, cancer, wounds, allergies, toothache, leprosy, bronchitis, epilepsy, hemorrhoids, leukoderma and rheumatoid arthritis. C. caesia is one of the important species of Curcuma which possess various bioactive compounds that responsible for numerous pharmacological activities. The rhizome which is the most prominent feature of the plant is rich with essential oil. In addition, the leaves of this species also consist of essential oil with various bioactive compounds. This review article is aimed to discuss in-depth on botany, ethnomedicinal uses, geographical distribution, propagation, phytochemical studies, pharmacological activities and toxicity of C. caesia. The phytochemical studies revealed that a total of 17 functional groups were detected from rhizome extract of C. caesia. The pharmacological studies conducted demonstrated that C. caesia extract exhibited anti-acne, analgesic, anthelmintic, anti-asthmatic, anti-inflammatory, anti-bacterial, anti-fungal, anti-diabetic, antiproliferative, anticancer, antiulcer, hepatotoxicity, nephrotoxicity, neurotoxicity and cytotoxicity effects. Furthermore, toxicity studies revealed that C. caesia extract is safe for consumption and does not cause toxicity.

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姜黄的民族医药用途、植物化学、药理特性和毒理学研究。回顾

姜黄(Curcuma caesia)或俗称黑姜黄，属于姜科。根茎是该物种最重要的部分，被广泛用作民间药物，用于治疗哮喘、发烧、癌症、伤口、过敏、牙痛、麻风病、支气管炎、癫痫、痔疮、白癜风和类风湿性关节炎。姜黄是姜黄属植物中重要的一种，具有多种生物活性物质，具有多种药理活性。根茎是这种植物最显著的特征，它含有丰富的精油。此外，该物种的叶子还含有具有各种生物活性化合物的精油。本文就其植物学、民族医药用途、地理分布、繁殖、植物化学研究、药理活性和毒性等方面进行了综述。植物化学研究表明，从茜草根茎提取物中共检测到17个官能团。药理研究表明，枸杞提取物具有抗痤疮、镇痛、驱虫药、平喘、抗炎、抗菌、抗真菌、抗糖尿病、抗增殖、抗癌、抗溃疡、肝毒性、肾毒性、神经毒性和细胞毒性作用。此外，毒性研究表明，茜草提取物是安全的消费，没有毒性。

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来源期刊

Advances in Traditional Medicine PHARMACOLOGY & PHARMACY-

CiteScore

4.30

自引率

0.00%

发文量

期刊介绍： Advances in Traditional Medicine (ADTM) is an international and peer-reviewed journal and publishes a variety of articles including original researches, reviews, short communications, and case-reports. ADTM aims to bridging the gap between Traditional knowledge and medical advances. The journal focuses on publishing valid, relevant, and rigorous experimental research and clinical applications of Traditidnal Medicine as well as medical classics. At the same time, the journal is devoted to communication among basic researcher and medical clinician interested in the advancement of Traditional Medicine. Topics covered by the journal are: Medical Classics & History; Biomedical Research; Pharmacology & Toxicology of Natural Products; Acupuncture & Moxibustion; Sasang Constitutional Medicine; Diagnostics and Instrumental Development; Clinical Research. ADTM is published four times yearly. The publication date of this journal is 30th March, June, September, and December.