Sexual and urinary function post-surgical treatment of femoroacetabular impingement: experience from the FIRST trial and embedded cohort study.

IF 1.4 4区 医学 Q3 ORTHOPEDICS
Journal of Hip Preservation Surgery Pub Date : 2022-01-21 eCollection Date: 2022-01-01 DOI:10.1093/jhps/hnac003
Pierre-Olivier Jean, Nicole Simunovic, Andrew Duong, Diane Heels-Ansdell, Olufemi R Ayeni
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Abstract

The goal of this study was to investigate the sexual and urinary function and any related complications in patients post-hip arthroscopy for the treatment of femoroacetabular impingement (FAI). Data from 214 patients enrolled in the FIRST trial and 110 patients enrolled in the trial's embedded prospective cohort study (EPIC) were analyzed. EPIC patients either refused to participate in the trial or did not meet the FIRST eligibility criteria. Outcomes included the International Consultation on Continence Questionnaire (ICIQ) for males (ICIQ-MLUTS) and females (ICIQ-FLUTS) and the Female Sexual Function Index (FSFI) and International Index of Erectile Function (IIEF) administered before surgery and at 6 weeks and 12 months. Urinary and sexual function adverse events were recorded up to 24 months. Linear regression analyses were conducted to compare the osteochondroplasty and lavage groups in the FIRST trial and to evaluate age and traction time as prognostic factors among all patients. Longer traction time was associated with a small but statistically significant improvement in urinary voiding function in males at 6 weeks and 12 months (MD (95% CI) = 0.25 (0.12, 0.39), P < 0.001 and 0.21 (0.07, 0.35), P = 0.004), respectively. Mean traction time was 43.7 (± 23.2) min for FIRST trial and 52.8 (± 15.2) min for EPIC cohort patients. Increasing age in male patients was associated with a decrease in urinary continence at 6 weeks (MD (95% CI) = 0.25 (-0.42, -0.09), P = 0.003). FIRST male patients who received osteochondroplasty improved significantly in sexual function at 12 months compared to males in the EPIC cohort (MD (95% CI) = 2.02 (0.31, 3.72), P = 0.020). There was an overall complication rate of 1.2% at 24 months [one urinary infection, two instances of erectile dysfunction (one transient and one ongoing at 24 months) and one reported transient numbness of tip of the penis]. Hip arthroscopy for the treatment of FAI has a low rate of sexual and urinary dysfunction and adverse events.

股骨髋臼撞击术后的性功能和泌尿功能治疗:来自FIRST试验和嵌入式队列研究的经验
本研究的目的是探讨髋关节镜治疗股骨髋臼撞击(FAI)后患者的性功能和泌尿功能及其相关并发症。我们分析了214名入组FIRST试验患者和110名入组该试验的嵌入前瞻性队列研究(EPIC)患者的数据。EPIC患者要么拒绝参加试验,要么不符合FIRST资格标准。结果包括男性(ICIQ- mluts)和女性(ICIQ- fluts)的国际失禁咨询问卷(ICIQ),以及术前、6周和12个月的女性性功能指数(FSFI)和国际勃起功能指数(IIEF)。泌尿和性功能不良事件记录长达24个月。采用线性回归分析比较FIRST试验中骨软骨成形术组和灌洗组,并评估所有患者的年龄和牵引时间作为预后因素。较长的牵引时间与6周和12个月时男性排尿功能的改善有关(MD (95% CI)分别= 0.25 (0.12,0.39),P < 0.001和0.21 (0.07,0.35),P = 0.004)。FIRST试验的平均牵引时间为43.7(±23.2)min, EPIC队列患者的平均牵引时间为52.8(±15.2)min。男性患者年龄的增加与6周时尿失禁的减少相关(MD (95% CI) = 0.25 (- 0.42, - 0.09), P = 0.003)。与EPIC队列中的男性相比,接受骨软骨成形术的FIRST男性患者在12个月时的性功能显著改善(MD (95% CI) = 2.02 (0.31, 3.72), P = 0.020)。24个月时,总并发症发生率为1.2%[1例尿路感染,2例勃起功能障碍(1例短暂性,1例持续24个月),1例报告阴茎尖端短暂性麻木]。髋关节镜治疗FAI的性、尿功能障碍和不良事件发生率低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
自引率
20.00%
发文量
45
审稿时长
12 weeks
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