Efficacy of Ipsilateral, Focal-Simple Limbal Epithelial Transplantation for Large Primary Nasal Pterygia Treatment

S. Thatte, Y. Goyal
{"title":"Efficacy of Ipsilateral, Focal-Simple Limbal Epithelial Transplantation for Large Primary Nasal Pterygia Treatment","authors":"S. Thatte, Y. Goyal","doi":"10.12974/2309-6136.2021.09.1","DOIUrl":null,"url":null,"abstract":"Purpose: The long-term success of pterygium surgery is subject to treatment of the limbal stem cell defect. The purpose of this study is to present an alternative method to conjunctival autografting in patients with large pterygia and consequently a large limbal stem cell defect.\nMethods: 38 Patients with primary nasal pterygium of more than 5 mm limbal involvement were selected for the procedure. Simple limbal epithelial transplantation with human amniotic membrane graft placement over the bare sclera after pterygium excision was done. Patients were followed-up for a period of 12 months.\nResults: From post-operative day 7, patients had significant improvement in complaints and ocular surface morphology. We reported only one case of graft failure which was a consequence of patient’s non-compliance with post-operative medications and follow-up.\nConclusion: Focal-simple limbal epithelial transplantation is an effective alternative to conjunctival limbal autografting in patients with large pterygia where preservation of virgin conjunctiva is prudent for future ocular surgeries. ","PeriodicalId":73874,"journal":{"name":"Journal of ocular diseases and therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of ocular diseases and therapeutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12974/2309-6136.2021.09.1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose: The long-term success of pterygium surgery is subject to treatment of the limbal stem cell defect. The purpose of this study is to present an alternative method to conjunctival autografting in patients with large pterygia and consequently a large limbal stem cell defect. Methods: 38 Patients with primary nasal pterygium of more than 5 mm limbal involvement were selected for the procedure. Simple limbal epithelial transplantation with human amniotic membrane graft placement over the bare sclera after pterygium excision was done. Patients were followed-up for a period of 12 months. Results: From post-operative day 7, patients had significant improvement in complaints and ocular surface morphology. We reported only one case of graft failure which was a consequence of patient’s non-compliance with post-operative medications and follow-up. Conclusion: Focal-simple limbal epithelial transplantation is an effective alternative to conjunctival limbal autografting in patients with large pterygia where preservation of virgin conjunctiva is prudent for future ocular surgeries. 
单侧、局灶性单纯四肢上皮移植治疗原发性大面积鼻翼痛的疗效观察
目的:翼状胬肉手术的远期成功与否取决于角膜缘干细胞缺损的治疗。本研究的目的是提出一种自体结膜移植的替代方法,用于治疗大面积翼状胬肉患者,从而导致大面积角膜缘干细胞缺损。方法:选择38例累及鼻翼缘大于5mm的原发性鼻翼状胬肉患者进行手术治疗。翼状胬肉切除后,行单纯角膜缘上皮移植,人羊膜移植物置于裸巩膜上。患者随访12个月。结果:从术后第7天起,患者的主诉和眼表形态均有显著改善。我们只报告了一例由于患者不遵守术后药物治疗和随访而导致的移植物衰竭。结论:单纯性角膜缘上皮移植是大翼状胬肉患者自体结膜移植的有效替代方法,在未来的眼科手术中,保留原始结膜是谨慎的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信