Linear IgA-bullous dermatosis in a child during martial law. Clinical case

Abstract

Linear IgA-bullous dermatosis (chronic childhood disease) - a rare autoimmune subepithelial vesiculobulular disease caused by the formation of IgA autoantibodies, directed against various hemidesmosomal antigens, which is more common in children of early preschool age. Purpose - is to describe our own clinical observation of a case of linear IgA-bullous dermatosis in a girl aged 2 years 9 months to increase the level of alertness of doctors regarding this pathology in children, especially at an early age. Clinical case. At the time of admission her condition was of moderate severity due to the presence of a confluent papular-vesicular rash located on the face, neck, limbs. The rash was accompanied by the development of erosions surrounded by a ring of vesicles and caused a feeling of discomfort, severe itching. During local treatment and systemic antifungal tablets, the child’s condition improved, however, complete remission was not achieved after 7 week of the therapy, new bullas appeared. Additional diagnostic investigation allowed to suppose the diagnosis linear IgA - bullous dermatosis. Adjustment of therapy was made (steroids per os administration) and the child's condition improved gradually in a month. The research was carried out in accordance with the principles of the Helsinki Declaration. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the authors.