⁶⁸Ga-PSMA-11 PET/CT in Bilateral Clear Cell Renal Cell Carcinoma: an Intra-patient Comparison Between High and Low Grade Tumors.

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Nuclear Medicine and Molecular Imaging Pub Date : 2023-12-01 Epub Date: 2023-04-24 DOI:10.1007/s13139-023-00805-6

Luca Urso, Giovanni Christian Rocca, Grazia Maria Conti, Alessandro Colella, Alberto Nieri, Corrado Cittanti, Carmelo Ippolito, Mirco Bartolomei

引用次数: 0

Abstract

Recent studies have outlined the emerging role of ⁶⁸Ga-PSMA-11 PET/CT in the diagnostic algorithm of clear cell renal cell carcinoma (ccRCC). We report a unique intra-patient comparison of bilateral primary ccRCC imaged with ⁶⁸Ga-PSMA-11 PET/CT. Although both tumors resulted ⁶⁸Ga-PSMA-11 avid, we found a remarkable discrepancy in uptake intensity between the high grade and the low grade ccRCC. This case confirms previous evidence reporting that SUVmax on ⁶⁸Ga-PSMA-11 PET/CT could be used to discriminate aggressive high grade from more indolent low grade ccRCC, due to their different endothelial expression of PSMA.

查看原文本刊更多论文

68Ga-PSMA-11 PET/CT在双侧透明细胞肾细胞癌中的应用:高分级和低分级肿瘤的患者内比较

最近的研究概述了68Ga-PSMA-11 PET/CT在透明细胞肾细胞癌(ccRCC)诊断算法中的新作用。我们报告了一项独特的68Ga-PSMA-11 PET/CT双侧原发性ccRCC的患者内比较。尽管这两种肿瘤都产生了68Ga-PSMA-11的摄取，但我们发现高级别和低级别ccRCC在摄取强度上存在显著差异。该病例证实了先前的证据报道，68Ga-PSMA-11 PET/CT上的SUVmax可用于区分侵袭性高级别ccRCC和较惰性低级别ccRCC，因为它们的内皮细胞PSMA表达不同。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Nuclear Medicine and Molecular Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

2.20

自引率

7.70%

发文量

期刊介绍： Nuclear Medicine and Molecular Imaging (Nucl Med Mol Imaging) is an official journal of the Korean Society of Nuclear Medicine, which bimonthly publishes papers on February, April, June, August, October, and December about nuclear medicine and related sciences such as radiochemistry, radiopharmacy, dosimetry and pharmacokinetics / pharmacodynamics of radiopharmaceuticals, nuclear and molecular imaging analysis, nuclear and molecular imaging instrumentation, radiation biology and radionuclide therapy. The journal specially welcomes works of artificial intelligence applied to nuclear medicine. The journal will also welcome original works relating to molecular imaging research such as the development of molecular imaging probes, reporter imaging assays, imaging cell trafficking, imaging endo(exo)genous gene expression, and imaging signal transduction. Nucl Med Mol Imaging publishes the following types of papers: original articles, reviews, case reports, editorials, interesting images, and letters to the editor. The Korean Society of Nuclear Medicine (KSNM) KSNM is a scientific and professional organization founded in 1961 and a member of the Korean Academy of Medical Sciences of the Korean Medical Association which was established by The Medical Services Law. The aims of KSNM are the promotion of nuclear medicine and cooperation of each member. The business of KSNM includes holding academic meetings and symposia, the publication of journals and books, planning and research of promoting science and health, and training and qualification of nuclear medicine specialists.

文献相关原料

公司名称	产品信息	采购帮参考价格

68Ga-PSMA-11 PET/CT in Bilateral Clear Cell Renal Cell Carcinoma: an Intra-patient Comparison Between High and Low Grade Tumors.

Abstract

⁶⁸Ga-PSMA-11 PET/CT in Bilateral Clear Cell Renal Cell Carcinoma: an Intra-patient Comparison Between High and Low Grade Tumors.