Spontaneous medication-related osteonecrosis of the jaws in a 23-year-Old

Q3 Dentistry

Oral and Maxillofacial Surgery Cases Pub Date : 2023-03-01 DOI:10.1016/j.omsc.2022.100289

Brenden J. Manley, Timothy W. Neal, Shyam Indrakanti, Thomas Schlieve

引用次数: 2

Abstract

Medication-related osteonecrosis is a well-documented yet rare complication of antiresorptive treatment. The risk of MRONJ is well established in the adult population but has yet to be established in the pediatric population. Additionally, the risk to this population in adulthood following many years of antiresorptive use is unknown. This case report describes a patient who received long-term antiresorptive medication as an adolescent and spontaneously developed MRONJ at age 23. To the authors’ knowledge, this is the youngest patient with MRONJ reported in the literature.

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一例23岁患者的自发药物相关颌骨坏死

药物相关性骨坏死是一种文献记载良好但罕见的抗吸收治疗并发症。MRONJ的风险在成人人群中已经确定，但在儿科人群中尚未确定。此外，该人群在使用抗吸收药物多年后成年后的风险尚不清楚。本病例报告描述了一名患者在青少年时期接受长期抗吸收药物治疗，并在23岁时自发发展为MRONJ。据作者所知，这是文献中报道的最年轻的MRONJ患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oral and Maxillofacial Surgery Cases Medicine-Otorhinolaryngology

CiteScore

0.60

自引率

0.00%

发文量

审稿时长

69 days

期刊介绍： Oral and Maxillofacial Surgery Cases is a surgical journal dedicated to publishing case reports and case series only which must be original, educational, rare conditions or findings, or clinically interesting to an international audience of surgeons and clinicians. Case series can be prospective or retrospective and examine the outcomes of management or mechanisms in more than one patient. Case reports may include new or modified methodology and treatment, uncommon findings, and mechanisms. All case reports and case series will be peer reviewed for acceptance for publication in the Journal.