Laboratory diagnosis of Trypanosoma cruzi infection: a narrative review

Constanza Lopez-Albizu, Rocio Rivero, G. Ballering, H. Freilij, M. S. Santini, M. Bisio
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引用次数: 1

Abstract

Trypanosoma cruzi infection, currently endemic in 21 countries, is a public health problem not only in the Americas but also in countries with Latin American migrants. However, it is estimated that two-thirds of people with Chagas disease currently live in urban areas and that only 10% of them are aware of it. This review summarizes the most important aspects of the diagnosis of human T. cruzi infection by describing the following aspects of clinical laboratory diagnosis: the most widely used tests available in Latin America and those expected to improve access to diagnosis of the affected population with their implementation; the advantages, disadvantages, and sensitivity of the tests in the different phases of infection; and their usefulness in the acute or chronic phases of infection and in the context of immunosuppression. In this way, we hope to contribute to broadening the knowledge about this prevalent infection in the Americas. Graphical Abstract
克氏锥虫感染的实验室诊断:述评
克氏锥虫感染目前在21个国家流行,不仅在美洲而且在有拉丁美洲移民的国家都是一个公共卫生问题。然而,据估计,目前三分之二的恰加斯病患者生活在城市地区,其中只有10%的人意识到这一点。本综述通过描述临床实验室诊断的以下方面,总结了人类克氏t型病毒感染诊断的最重要方面:拉丁美洲可用的最广泛使用的检测方法,以及那些有望通过实施改善受影响人群获得诊断的检测方法;在感染的不同阶段检测的优点、缺点和敏感性;以及它们在感染的急性或慢性阶段以及免疫抑制的情况下的作用。通过这种方式,我们希望有助于扩大对美洲这种流行感染的认识。图形抽象
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