Established and new treatment roadmaps for pleural mesothelioma: opinions of the Turkish Collaborative Group

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Applied Bio Materials Pub Date : 2023-09-27 DOI:10.1016/j.currproblcancer.2023.101017

Muhammet Ali Kaplan , Mehmet Ali Nahit Şendur , Ayten Kayı Cangır , Pınar Fırat , Erdem Göker , Saadettin Kılıçkap , Başak Oyan , Ayşim Büge Öz , Feyyaz Özdemir , Gökhan Özyiğit

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引用次数: 0

Abstract

Pleural mesothelioma (PM) is a cancer of the pleural surface, which is aggressive and may be rapidly fatal. PM is a rare cancer worldwide, but is a relatively common disease in Turkey. Asbestos exposure is the main risk factor and the most common underlying cause of the disease. There have been significant improvements in diagnoses and treatments of many malignancies; however, there are still therapeutic challenges in PM. In this review, we aimed to increase the awareness of health care professionals, oncologists, and pulmonologists by underlining the unmet needs of patients with PM and by emphasizing the need for a multidisciplinary treatment and management of PM. After reviewing the general information about PM, we further discuss the treatment options for patients with PM using immunotherapy and offer evidence for improvements in the clinical outcomes of these patients because of these newer treatment modalities.

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胸膜间皮瘤的既定和新的治疗路线图：土耳其合作小组的意见。

胸膜间皮瘤（PM）是一种胸膜表面的癌症，具有侵袭性，可能迅速致命。PM是全球罕见的癌症，但在土耳其是一种相对常见的疾病。石棉暴露是该疾病的主要危险因素和最常见的潜在原因。许多恶性肿瘤的诊断和治疗都有了显著的改进；然而，PM仍然存在治疗挑战。在这篇综述中，我们旨在通过强调PM患者未满足的需求，并强调对PM进行多学科治疗和管理的必要性，提高卫生保健专业人员、肿瘤学家和肺科医生的认识。在回顾了有关PM的一般信息后，我们进一步讨论了使用免疫疗法治疗PM患者的选择，并为这些新的治疗方式改善这些患者的临床结果提供了证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464