Mood Impairment in Patients with Olfactory Loss Predicts a More Pronounced Recovery of Olfactory Function.

IF 2 4区医学 Q2 OTORHINOLARYNGOLOGY

Orl-Journal for Oto-Rhino-Laryngology Head and Neck Surgery Pub Date : 2024-01-01 Epub Date: 2023-10-16 DOI:10.1159/000533629

Agnieszka Sabiniewicz, Thomas Hummel

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引用次数: 0

Abstract

Background: Here, we refer to our publication "Symptoms of depression change with olfactory function" [Sci Rep. 2022 Apr 5;12(1):5656].

Objectives: Depression decreases with olfactory improvement, but the question remains open of whether patients who indicate more suffering regarding mood impairment exhibit a different pattern of recovery from olfactory loss compared to those who suffer less.

Method: In the course of an additional investigation of our previously published dataset, we established groups of participants (N = 171) with low (≤8 points on a depression [ADSL] scale; 47%; n = 45) and high (≥14 points on ADSL scale; 53%; n = 53) mood impairment.

Results: We found that the group that reported more sufferance on a depression [ADSL] scale improved more in change of olfactory function, and, more importantly, odor discrimination change over a period of an average of 11 months.

Conclusion: Patients, who suffered more, as indicated by higher scores on ADSL scale, may have been more willing to commit to the study protocol, and thus their improvement was more notable.

查看原文本刊更多论文

嗅觉丧失患者的情绪障碍预测嗅觉功能更明显的恢复。

背景：在这里，我们参考了我们的出版物“抑郁症状随嗅觉功能的变化而变化”[Sci.Rep.2022 Apr 5；12（1）:55656]。目的：抑郁随着嗅觉的改善而减少，但问题仍然是，与情绪障碍患者相比，情绪障碍患者是否表现出不同的嗅觉丧失恢复模式。方法：在对我们之前发表的数据集进行额外调查的过程中，我们建立了一组参与者（N=171），他们的情绪障碍程度低（在抑郁症[ADSL]量表上≤8分；47%；N=45）和高（在ADSL量表上≥14分；53%；N=53）。结果：我们发现，在平均11个月的时间里，在抑郁[ADSL]量表上报告更多经历的组在嗅觉功能的变化方面改善得更多，更重要的是，气味辨别能力的变化也改善得更多。结论：ADSL量表得分较高的患者可能更愿意遵守研究方案，因此他们的改善更显著。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Orl-Journal for Oto-Rhino-Laryngology Head and Neck Surgery 医学-耳鼻喉科学

CiteScore

2.80

自引率

7.70%

发文量

审稿时长

6-12 weeks

期刊介绍： ''ORL'' contains concise, original scientific papers of interest for both clinicians and researchers in oto-rhino-laryngology and head and neck surgery. Contributions drawn from the basic sciences cover new knowledge on the anatomy, pathology, pathophysiology, immunology and tumor biology of head and neck and the auditory and vestibular system, the salivary glands, paranasal sinuses and of the organs of the upper respiratory and digestive tract. The practical value of the journal is accentuated by reports of clinical progress in diagnosis and therapy.