Following the Birth, Life, and Death of mRNAs in Single Cells.

IF 11.4 1区生物学 Q1 CELL BIOLOGY

Annual review of cell and developmental biology Pub Date : 2023-10-16 DOI:10.1146/annurev-cellbio-022723-024045

Bastian T Eichenberger, Esther Griesbach, Jessica Mitchell, Jeffrey A Chao

引用次数: 0

Abstract

Recent advances in single-molecule imaging of mRNAs in fixed and living cells have enabled the lives of mRNAs to be studied with unprecedented spatial and temporal detail. These approaches have moved beyond simply being able to observe specific events and have begun to allow an understanding of how regulation is coupled between steps in the mRNA life cycle. Additionally, these methodologies are now being applied in multicellular systems and animals to provide more nuanced insights into the physiological regulation of RNA metabolism.

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单细胞中信使核糖核酸的产生、生存和死亡。

固定细胞和活细胞中信使核糖核酸单分子成像的最新进展使信使核糖核酸的生命能够以前所未有的空间和时间细节进行研究。这些方法已经超越了简单地观察特定事件的能力，并开始了解mRNA生命周期中各步骤之间的调节是如何耦合的。此外，这些方法现在正在多细胞系统和动物中应用，以对RNA代谢的生理调节提供更细致的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annual review of cell and developmental biology 生物-发育生物学

CiteScore

19.50

自引率

0.00%

发文量

期刊介绍： The Annual Review of Cell and Developmental Biology, established in 1985, comprehensively addresses major advancements in cell and developmental biology. Encompassing the structure, function, and organization of cells, as well as the development and evolution of cells in relation to both single and multicellular organisms, the journal explores models and tools of molecular biology. As of the current volume, the journal has transitioned from gated to open access through Annual Reviews' Subscribe to Open program, making all articles published under a CC BY license.