Surface Plasmon Resonance Biosensor Based on STO and Graphene Sheets for Detecting Two Commonly Used Buffers: TRIS–Borate-EDTA and Dulbecco Phosphate Buffered Saline

IF 3.3 4区物理与天体物理 Q2 CHEMISTRY, PHYSICAL

Plasmonics Pub Date : 2023-05-29 DOI:10.1007/s11468-023-01894-x

Sofyan A. Taya, Nael Doghmosh, Abdulkarem H. M. Almawgani, Ayman Taher Hindi, Ilhami Colak, Anas A. M. Alqanoo, Shobhit K. Patel, Amrindra Pal

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引用次数: 7

Abstract

In this study, we present a new biosensor based on surface plasmon resonance (SPR) for the detection of two commonly used buffers: Dulbecco Phosphate Buffered Saline (PBS) and TRIS-Borate-EDTA Buffer (TBE). The proposed SPR sensor utilizes a combination of SrTiO₃ (STO) and two-dimensional (2D) materials. In the angle interrogation method, using STO can almost double the sensitivity compared to using traditional SPR biosensors. Moreover, using a single sheet of graphene (SSG) can further improve the sensitivity. For PBS and TBE buffers, the highest sensitivities reached are 327.023 and 320.581°/RIU with the structures SSG/35 nm Ag/ 14 nm STO and SSG/50 nm Ag/12 nm STO, respectively. We also investigate a set of 2D nanomaterials and found that the maximum sensitivity can be attained with WSe₂ due to its lower real part of the refractive index. The results reveal that the proposed SPR biosensor is an efficient tool for biomedical applications.

查看原文本刊更多论文

基于STO和石墨烯片的表面等离子体共振生物传感器用于检测两种常用缓冲液：TRIS–硼酸盐-EDTA和Dulbecco磷酸盐缓冲液

在本研究中，我们提出了一种基于表面等离子体共振（SPR）的新型生物传感器，用于检测两种常用的缓冲液：Dulbecco磷酸盐缓冲液（PBS）和TRIS硼酸盐EDTA缓冲液（TBE）。所提出的SPR传感器利用SrTiO3（STO）和二维（2D）材料的组合。在角度询问方法中，与使用传统SPR生物传感器相比，使用STO几乎可以将灵敏度提高一倍。此外，使用单片石墨烯（SSG）可以进一步提高灵敏度。对于PBS和TBE缓冲液，结构为SSG/35nm Ag/14nm STO和SSG/50nm Ag/12nm STO的最高灵敏度分别为327.023和320.581°/RIU。我们还研究了一组2D纳米材料，发现WSe2由于其折射率的实部较低，可以获得最大的灵敏度。结果表明，所提出的SPR生物传感器是一种有效的生物医学应用工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Plasmonics 工程技术-材料科学：综合

CiteScore

5.90

自引率

6.70%

发文量

164

审稿时长

2.1 months

期刊介绍： Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons. Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.